Neuro 3 Cortex Anatomy + Lesions (pg.460FA15)

Question 1

Syndrome caused by lesion to dominant angular gyrus in parietal lobe

Answer 1

Gerstmann syndrome

Question 2

Syndrome with these symptoms:

• Agraphia
• Acalculia
• Right-left disorientation
• Finger agnosia

Answer 2

Gerstmann syndrome

Question 3

The inability to express emotion or inflection in speech. Caused by lesion on non-dominant side of brain.

Answer 3

Dysprosody

*Usually on opposite side as Brocas - same area

Question 4

Lesion on non-dominant parietal lobe causing one to notice half their body (for ex)

Answer 4

Hemispatial neglect

Question 5

Which way do the eyes move during a frontal eye field lesion?

Answer 5

Eyes look toward the lesion

Question 6

Which way do the eyes move when PPRF is damaged?

Answer 6

Eyes look away from the lesion

*Paramedian Pontine Reticular Formation: Brainstem (responsible for scanning eye movements)

Question 7

This syndrome won’t allow pts to look up

Answer 7

Parinaud’s syndrome

Question 8

Lesions of this colliculus causes paralysis of upward gaze

Answer 8

Superior colliculus

Parinaud’s syndrome= pts look downward away from superior lesion

Question 9

Bilateral hippocampal lesions result in what symptom?

Answer 9

Anterograde amnesia

*No new memories

Question 10

Lesions to these structures is caused by thiamine deficiency and can cause Wernicke-Korsakoff syndrome

Answer 10

Mamillary bodies

*often due to low B1/ETOH

Question 11

Damage to which artery causes Broca’s or Wernicke’s aphasia?

Answer 11

Middle Cerebral a

Question 12

Damage to which artery causes Unilateral lower extremity sensory and/or motor loss?

Answer 12

Anterior Cerebral a

Question 13

Damage to which artery causes Unilateral sensory and/or motor loss in the face and arm?

Answer 13

Middle Cerebral a

Question 14

Several berry aneurysms in Circle of Willis + kidney issues

Answer 14

Autosomal dominant polycystic kidney Dz

Question 15

Kluver-Bucy syndrome is caused by bilateral lesions of the

Answer 15

Amygdala

Question 16

Basal ganglia lesions result in movement disorders T/F?

Answer 16

True

Question 17

Hypokinesis seen in Parkinson Dz is caused by a lesion in this area

Answer 17

Basal ganglia

Question 18

Hyperkinesis and chorea seen in Huntington’s is caused by a lesion in this area

Answer 18

Basal ganglia

Question 19

Hemiballismus is caused by a lesion to which specific area of the Basal ganglia?

Answer 19

Subthalamic nucleus

Question 20

What is Hemiballismus?

Answer 20

Flailing one arm involuntarily

Question 21

Hemispheric Cerebellar lesions cause what symptoms?

Answer 21

Ipsilateral movement disorders

• Limb ataxia
• Intention tremor

Question 22

Cerebellar vermis lesions affect which structures? (give a general answer)

Answer 22

Midline structures

Question 23

Truncal ataxia is caused by lesion to which structure?

Answer 23

Cerebellar vermis

Question 24

Slurred speech caused by loss of movement to middle of lips and middle of tongue may be caused by a lesion in this structure

Answer 24

Cerebellar vermis

*Affects midline structures (because it is itself a midline structure maybe?)

Question 25

Slurred speech is also called

Answer 25

Dysarthria

Question 26

Which type of collagen is affected in Classical Ehlers-Danlos syndrome?

Answer 26

Type V and Type I Collagen

Question 27

Which type of collagen is affected in Vascular Ehlers-Danlos syndrome?

Answer 27

Type III Collagen

Question 28

Which type of collagen is affected in Osteogenesis imperfecta?

Answer 28

Type I Collagen

Question 29

Lesions of this Midbrain area can cause reduced arousal and coma

Answer 29

Reticular activating system

Question 30

Associated with HSV-1. Syndrome is disinhibition behavior - hyperphagia - hypersexuality - hyperorality

Answer 30

Kluver-Bucy Syndrome *Amygdala