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Antivirals SM > Neuraminidase > Flashcards

Neuraminidase Flashcards

1
Q

Oseltamivir / Zanamivir
MOA

A

Inhibits viral replication / release by inhibiting neuraminidase which is necessary for viral release

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2
Q

Oseltamivir / Zanamivir
Abs/Distrb/Elim

A

Given orally – within 48h of onset of symptoms for post-exposure prophylaxis.
Zanamivir is given intranasally.

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3
Q

Oseltamivir / Zanamivir
Clinical use

A

Prevention and treatment of infections with inuenza viruses A and B.

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4
Q

Oseltamivir / Zanamivir
Adverse Effects

A

GIT disturbances, headache, dizziness, rashes; very rarely hepatitis.

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Antivirals SM (7 decks)

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