HIV Integrase Inhibitor Flashcards

1
Q

Raltegravir
MOA

A

Antagonistically binds HIV integrase and prevents its binding to 3’-LTRs. This prevents viral DNA insertion and thus viral mRNA transcription.

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2
Q

Raltegravir
Abs/Distrb/Elim

A

Oral tablets

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3
Q

Raltegravir
Clinical use

A

HIV-1 infection

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4
Q

Raltegravir
Adverse effects

A
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