HIV Integrase Inhibitor Flashcards
1
Q
Raltegravir
MOA
A
Antagonistically binds HIV integrase and prevents its binding to 3’-LTRs. This prevents viral DNA insertion and thus viral mRNA transcription.
2
Q
Raltegravir
Abs/Distrb/Elim
A
Oral tablets
3
Q
Raltegravir
Clinical use
A
HIV-1 infection
4
Q
Raltegravir
Adverse effects
A