Nervous System Test Flashcards
What is a concentration gradient?
Difference between concentration of a substance in two compartments
How do you calculate the concentration gradient?
ION(out) - ION(in)
What is excitability?
The ability of a cell to send and receive electrical signals across the plasma membrane
What does it mean to move down the concentration gradient?
From high to low concentration
What does it mean to move up the concentration gradient?
From low to high concentration
What is electrostatic repulsion?
When like charges repel
What is equilibrium potential?
There is no net flux (no change in the ion concentration)
What is an action potential?
A Rapid sequence of changes in the voltage across a membrane
What are the steps of an action potential? (start to finish)
- Na+ gates open allowing Na+ to enter and depolarize the cell.
- The neuron reaches threshold and an action potential is propagated along the axon.
- The action potential peaks and Na+ gates close.
- K+ gates open and K+ exits the cell causing repolarization of the cell.
- K+ efflux and the Na+/K+ pump cause hyperpolarization of the cell.
- Natural leaky cells establish resting membrane potential.
What are dendrites?
The site of signal input
What is the soma?
Cell body
What happens at the axon hillock?
Action potential is generated
What is an axon?
The long string like part of the neuron that signals are sent down
What is the axon terminal?
The site of signal output
What is a synaptic cleft?
The gap between two cells filled with interstitial fluid
What is a postsynaptic cell
The neuron located after the synapse that receives the signal
What is a graded potential?
A change in the electrical potential on the membrane of an excitable cell
What are the three channels present in the axon hillock?
K+ voltage gated channels
K+ leak channels
Na+ voltage gated channels
What are the two types of circuits?
Converging and diverging
Where does a converging circuit start?
A converging circuit starts in the PNS (sensory impulse)
Where does diverging circuit start?
Starts in the CNS (motor impulse)
What does a motor tract do?
Send signals from CNS to PNS
What does a sensory tract do?
Send a signal from PNS to brain (located in CNS)
What are the main two organs of the CNS?
The brain and spinal cord
What are 90% of the cells in the CNS?
Neuroglia
What are 10% of the cells in the CNS?
Neurons
What is the CNS supported by?
Cerebral spinal fluid (CSF)
What is an Axon?
Long thread like part of the neuron which impulses are sent from one cell body to another
What is the meninges?
A protective structure for the CNS
What are the three layers of the meninges? (superficial to deep)
- Dura mater
- Arachnoid mater
- Pia mater
What are the qualities of the Dura mater?
Thick, strong connective tissue layer
What are the qualities of the Arachnoid mater?
Thin, transparent fibrous membrane
What are the qualities of the Pia mater?
Delicate connective tissue layer
What are the functions of cerebrospinal fluid?
- Homeostatic regulation
- Support and cushioning
- Chemical and immunological buffering
What is the function of ventricles?
- Store CSF
- Provide a continuous flow of CSF between the brain and spinal cord
How does CSF move through the brain?
Ventricles
How is CSF produced?
Specialized tissues called choroid plexus and ependymal cells
What is the function of the blood brain barrier?
Tightly regulate the movement of ions, molecules, and cells between the blood and the brain
What type of cell is a neuron?
An excitable cell
What are graded potentials in dendrites called?
Synaptic potentials
What are the two types of synaptic potentials in dendrites?
EPSP and IPSP
- Excitatory
- Inhibitory
What is the function of neuroglia?
Regulate the internal environment of the CNS
What is the function of oligodendrocytes?
Create myelin sheath surrounding neurons in the CNS
What is the function of astrocytes?
- Neurotransmitter secretion/absorption
- Glycogenesis
- Fluid regulation
- Release of ATP
What is the function of ependymal cells?
Secrete CSF
What is the function of microglia?
- Remove damaged neurons
- Recognize infectious agents
- Prevent inflammation
What are the main function of the CNS?
- Process external sensory information
- Integrate information from a wide range of sources
- Send signals that control tissues in the body
- Consciousness perception of senses, memory, reason
What are three qualities of the spinal cord?
- Long thin tube
- Carry information to and from the brain
- Encased in vertebrae and meninges
What are dermatomes?
Locations where the body senses information
What are myotomes?
Muscle locations around the spinal cord
What are gyri?
Elevated ridges or hills
What are sulci?
Small grooves or valleys
What are fissures?
Deep grooves or canyons
What is the function of fibers?
Carry information within and between hemispheres
What is the function of association fibers?
Connect within one cortex
What is the function of commissural fibers?
Connect two cerebral hemispheres together
What is the function of projection fibers?
Connect cerebrum to other parts of the CNS and spinal cord
What is the medulla oblongata?
The relay station between the spinal cord and brain
What is the pons?
The relay station from medulla to higher cortical structures of the brain
What is the midbrain?
A nerve pathway of the cerebral hemisphere
What is the function of the cerebellum?
Controls BALANCE, eye movements, posture, learning complex movements, planning
What are the three parts of the diencephalon?
1) Thalamus
2) Epithalamus
3) Hypothalamus
What is the function of the thalamus?
Sensory relay center in our body
What is the function of the epithalamus?
Emotional and visceral responses
What is the function of the hypothalamus?
Regulation of homeostasis
What are the three parts of the cerebrum?
1) Cerebral cortex
2)Precentral gyrus
3) Postcentral gyrus
What is the function of the cerebral cortex?
Where complex processing information occurs
What is the function of the precentral gyrus?
Control of voluntary motor movement
What is the function of the postcentral gyrus?
Responsible for body awareness
What is the function of the hippocampus?
Learning and memory
What type of phase is sodium associated with?
The depolarization phase
What type of phase is potassium associated with?
The repolarization phase
What is the function of the frontal lobe?
Planning, motivation, and social judgement
What is the function of the cerebellum?
Balance and coordination
Do different areas of the brain communicate with each other?
Yes
- Difference areas of the brain DO communicate with each other
What are the three types of nerve fiber tracts?
1) Projection fibers
2) Commissural fibers
3) Association fibers
What is the function of commissural fibers?
Connect right and left hemispheres of the brain
What is the function of association fibers?
Connectv structures within the same hemisphere
What is the limbic system?
The emotional part of the brain
What is the function of the wernicke area?
Spoken and written language
What happens in the precentral gyrus?
Where motor somatosensory sense begin
What is the function of the vestibulospinal tracts?
Balance and posture
What is the function of reticulospinal tracts?
Locomotion and postural control
What is the function of rubrospinal tracts?
Primarily innervates muscles associated with flexion
What does innervate mean?
Supply with nerves
What are the three parts of a motor pathway?
1) Cerebral cortex
2) Spinal Cord
3) Skeletal muscles (or other effector organs)
Where do lower motor neurons originate?
The ventral horn
How do lower motor neurons correspond to different skeletal muscles?
They correspond ANATOMICALLY
What are the two types of motor neurons?
Alpha and gamma
What is the function of interneurons?
- Communication of neural impulses between neurons
- Allow for neural impulses to be relayed
What is the primary function of the motor cortex?
To generate signals to direct the movement of the body
What are the components of the motor cortex?
1) Primary motor cortex
2) Premotor cortex
3) Supplementary motor area
What is the function of the premotor cortex?
- Control muscle responses to visual or sound cues
- Stores motor memory
What is the function of the supplementary motor area?
Determine the amount of strength required for muscle movements
What is the function of the Primary motor cortex?
To generate signals to direct the movement of the body
What is the function of the upper motor neurons?
Carry the impulses for movement
What is the function of the cerebellum?
Adjust motor impulses to ensure muscle movements are precise and accurate
What is the function of muscle spindles?
Prevent overstretching or stretching too fast
What is the function of the golgi tendon organ?
The golgi tendon organ tells us how much tension the muscle is exerting