Nervous system Physiology (1) Flashcards
What is this an image of?
Nervous tissue
Label this neuron
List the parts that make up a neuron?
Cell body
Nucleus
Dendrites
Myelin Sheath
Node of Ranvier
Axon
Schwann’s Cells
Axon terminals
What is the cell body of a neuron?
Cell body, also known as the perikaryon (per -i-KAR-e ̄-on) or soma, contains a nucleus surrounded by cytoplasm that includes typical cellular organelles such as lysosomes, mitochondria, and a Golgi complex. Neuronal cell bodies also contain free ribosomes and prominent clusters of rough endoplasmic reticulum, termed Nissl bodies.
What is a dendrite?
The receiving or input portions of a neuron. The plasma membranes of dendrites (and cell bodies) contain numerous receptor sites for binding chemical messengers from other cells. Dendrites usually are short, tapering, and highly branched. In many neurons the dendrites form a tree-shaped array of processes extending from the cell body. Their cytoplasm contains Nissl bodies, mitochondria, and other organelles.
What is an axon?
A neuron propagates nerve impulses toward another neuron, a muscle fiber, or a gland cell.
An axon is a long, thin, cylindrical projection that often joins to the cell body at a cone-shaped elevation called the axon hillock. The part of the axon closest to the axon hillock is the initial segment. In most neurons, nerve impulses arise at the junction of the axon hillock and the initial segment, an area called the trigger zone, from which they travel along the axon to their destination. An axon contains mitochondria, microtubules, and neurofibrils.
Because rough endoplasmic reticulum is not present, protein synthesis does not occur in the axon. The cytoplasm of an axon, called axoplasm, is surrounded by a plasma membrane known as the axolemma (lemma sheath or husk).
What are neurons?
Neurons are electrically excitable cells, their function is to process and transmit information. Neurons communicate using electrical and chemical synapses (synaptic transmission)
The process that underlies electrical synaptic transmission is the action potential.
An action potential is an electrical signal that can be propagated through a nerve
An action potential is generated because the neuron membrane is electrically excitable.
Although neurons can occur in different shapes and sizes, they contain common structural elements
Describe the stucture of a neuron?
Soma (cell body)
- contains nucleus and other important material that provides for the life processes in the cell
Dendrites
- receive the messages between neurons
Axon
- links together the cell body and the terminal buttons
Terminal buttons (axon terminals)
- where the message is passed over to another neuron, across the synapse
What are each of these basic neurons?
How is an action potential created?
What is the cells resting potential?
It is the difference between the intra and extra cellular environments, that is exploited to produce an action potential.
The membrane has selective ion channels through which some ions, such as sodium (Na+), chloride (Cl-), potassium (K+) and calcium (Ca2+), can diffuse.
Neuronal membranes also use selective pumps to move ions against the concentration gradient
Because ions have electrical charge, the concentration gradient creates an electrical potential (about -70 millivolts) between the inside and the outside of the cell this is the cells resting potential
Explain what is happening in this diagram?
What are synapses?
These occur at the boundary of each nerve cell where it meets another nerve, muscle or endocrine cell.
The nerve impulse can be transmitted not only by an electrical signal but also by a chemical signal.
The substances which act as chemical signallers are called neurotransmitters.
Label this image
Where would electrical synapses typically be found?
- Anywhere, where a fast synchronous response is required for example:
- Retina
- Reflexes
- More interestingly they are found throughout the brain cortex and act in tandem with chemically driven neurotransmission.
- It is thought this gives the brain additional ‘plasticity’ because the mode of transmission is temporally different (chemical synapses are slower)*
Label this image
Name some common neurotransmitters
Acetylcholine
Norepinephrine
Dopamine
Serotonin
Glutamate
GABA- Gamma-Aminobutyric Acid
Enkephalins- Enk
What are the effects of the sympathetic and parasympathetic systems?
Most of your organs are supplied with both sympathetic and parasympathetic nerves
The two systems have opposing effects:
The sympathetic system is the “fight or flight” system
The parasympathetic system is in control in the normal relaxed state “rest and digest” system
Which system constricts the pupil?
Parasympathetic
Sympathetic dilates
Which system stimulates salivation?
Parasympathetic
Sympathetic inhibits salivation
Which system accelerates heart?
Sympathetic
Parasympathetic inhibits heart