Nervous System II - Synapses Flashcards

1
Q

Process by which many neurons project onto one postsynaptic neuron

A

Convergence

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2
Q

Two types of post-synaptic activation

A

EPSP - excitatory post synaptic potential IPSP - inhibitory post synaptic potential

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3
Q

EPSPs ___polarize the postsynaptic membrane

A

Depolarize

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4
Q

Two types of synapses

A
  1. Electrical 2. Chemical
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5
Q

Mechanisms of presynaptic modulation

A
  1. NT levels 2. Ca2+ levels 3. Presynaptic facilitation 4. Presynaptic inhibition
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6
Q

Synapse of an axon with another axon

A

Axoaxonic synapse

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7
Q

The adding effects of graded potentials are referred to as __________

A

Summation

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8
Q

Post synaptic activations are caused by ______ channel activation, leading to a change in __________

A

Ligand-gated channel activation (via NT) Leads to a change in postsynaptic potential

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9
Q

Synapses occur in which two locations

A
  1. Another neuron 2. Effector organs
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10
Q

Process by which one neuron projects onto many

A

Divergence

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11
Q

IPSPs ___polarize the postsynaptic membrane

A

Hyperpolarize

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12
Q

Two types of summation

A

Temporal and spatial

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13
Q
A
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14
Q

Eight phases of communication across a synapse from 1. Action potential to removal of NT (6-8)

A
  1. AP 2. Voltage-gated Ca2+ channels open 3. Ca2+ triggers vehicle exocytosis 4. NT diffuses into synapse and binds to receptor 5. Cellular response Removal of NT via: 6. Depredation 7. Reuptake 8. Diffusion
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15
Q

Inhibitory NTs cause ___ and ____ channels to open, causing ___ influx and ___ efflux

A

K+ and Cl- channels open; K+ efflux and Cl- influx

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16
Q

Synapse of an axon and a dendrite

A

Axodendritic synapse

17
Q

_____________: the summing of input from various synapses at the axon hillock of the post-synaptic neuron

A

Neural integration

18
Q

Synapse of an axon with a cell body

A

Axosomatic synapse

19
Q

Postsynaptic mechanisms (4)

A
  1. The many types of receptors for each type of NT 2. Receptor desensitization 3. Electrical state of postsynaptic membrane 4. Drugs and diseases
20
Q

How much is the synaptic delay between arrive of AP and change in postsynaptic Vm

A

0.5-5 mace

21
Q

Type of synapse that allows for presynaptic facilitation and inhibition

A

Axoaxonic

22
Q

The regulation of communication across a synapse

A

Presynaptic modulation

23
Q

Neural toxins that prevent inhibition

A

Tetanus, strychnine