Nervous System II - Synapses Flashcards
Process by which many neurons project onto one postsynaptic neuron
Convergence
Two types of post-synaptic activation
EPSP - excitatory post synaptic potential IPSP - inhibitory post synaptic potential
EPSPs ___polarize the postsynaptic membrane
Depolarize
Two types of synapses
- Electrical 2. Chemical
Mechanisms of presynaptic modulation
- NT levels 2. Ca2+ levels 3. Presynaptic facilitation 4. Presynaptic inhibition
Synapse of an axon with another axon
Axoaxonic synapse
The adding effects of graded potentials are referred to as __________
Summation
Post synaptic activations are caused by ______ channel activation, leading to a change in __________
Ligand-gated channel activation (via NT) Leads to a change in postsynaptic potential
Synapses occur in which two locations
- Another neuron 2. Effector organs
Process by which one neuron projects onto many
Divergence
IPSPs ___polarize the postsynaptic membrane
Hyperpolarize
Two types of summation
Temporal and spatial
Eight phases of communication across a synapse from 1. Action potential to removal of NT (6-8)
- AP 2. Voltage-gated Ca2+ channels open 3. Ca2+ triggers vehicle exocytosis 4. NT diffuses into synapse and binds to receptor 5. Cellular response Removal of NT via: 6. Depredation 7. Reuptake 8. Diffusion
Inhibitory NTs cause ___ and ____ channels to open, causing ___ influx and ___ efflux
K+ and Cl- channels open; K+ efflux and Cl- influx