Nervous System II Part 2

Question 1

Histamine is commonly known for its ______ actions

Answer 1

Paracrine

Question 2

ADHD causes lower glucose metabolism in areas of brain that control

Answer 2

Attention, movement

Question 3

Cholinergic fibres release…

Answer 3

Ach

Question 4

Amphetamines promote the release of?

Answer 4

Norepinephrine

Question 5

Adrenergic fibres are found in the _____, and _______________

Answer 5

CNS; neuromuscular junction between nerves and smooth muscle in autonomic nervous system

Question 6

Serotonin has ____ different receptor types

Answer 6

at least 16

Question 7

Schizophrenia is linked to excess….?

Answer 7

Dopamine

Question 8

Sleeping pills, anti-anxiety meds, and alcohol are all examples of ______ agonists

Answer 8

GABA

Question 9

Two types of receptors for ACH

Answer 9

Nicotinic and muscarinic

Question 10

Histamine is mostly located in the ______

Answer 10

Hypothalamus

Question 11

Parkinson’s is treated by administration of dopamine precursor…?

Answer 11

L-dopa

Question 12

Most common biogenic amines

Answer 12

Catecholamines

Question 13

Serotonin has an _____ effect involved in muscle control

Answer 13

excitatory

Question 14

Acetylcholine is synthesized from….

Answer 14

Acetyl CoA and choline

Question 15

__________ neurons contain dopamine

Answer 15

Dopaminergic

Question 16

Parkinson’s disease causes….?

Answer 16

Deficiency of dopamine in basal nuclei

Question 17

___________ results in degeneration of cholinergic neurons

Answer 17

Alzheimer’s

Question 18

Damage to ____ and _______ receptors are seen after stroke, brain trauma, hypoxic brain damage

Answer 18

glutamate and aspartate

Question 19

Dopaminergic neurons re present in the _______

Answer 19

substantia nigra and VTA of midbrain

Question 20

Drugs that bind to a receptor work in a similar action as NT are called?

Answer 20

Agonist

Question 21

______ is the most CNS inhibitory NT

Answer 21

GABA

Question 22

Agents that enhance GABA synaptic activity also ______ CNS activity

Answer 22

Depress

Question 23

Ephinephrine binds to ___ and ____ receptors

Answer 23

Alpha; beta

Question 24

Drugs that bind to a receptor and block NT are called?

Answer 24

Antagonists

Question 25

Highest serotonin activity seen during _____

Answer 25

Alert wakefulness

Question 26

Cell bodies for catecholamines lie in ________ and continue on to _______

Answer 26

Brain stem; branch extensively into all parts of brain and spinal cord

Question 27

Long term effects of cocaine at neural adaptation level

Answer 27

Desensitization of receptors, down regulation of receptors, decreased dopamine production

Question 28

Catecholamines play a major role in

Answer 28

States of consciousness, mood, motivation, directed attention

Question 29

Major transmitter in CNS and PNS

Answer 29

ACH

Question 30

Serotonin has important functions in regulation ______ and ________ mechanisms

Answer 30

Food intake and homeostatic mechanisms

Question 31

ADHD is characterized by a decreased blood flow and activity in the ______ cortex of the _______ lobe

Answer 31

Prefrontal cortex of the frontal lobes

Question 32

________ fibres contain norepinephrine

Answer 32

Adrenergic

Question 33

Glutamate and aspartate and ______ a.a.’s

Answer 33

excitatory

Question 34

Two major classes of adrenergic receptors

Answer 34

Alpha and beta

Question 35

ADHD is a deficiency in ______

Answer 35

NE and DA

Question 36

Biogenic Amines: synthesized from ____, and contain ______ group

Answer 36

Amino acids; amino group

Question 37

Cholinergic system plays major role in _______, _______ and ______

Answer 37

Attention, learning, memory

Question 38

Cocaine acts by… at synapse

Answer 38

Binds competitively with dopamine reuptake transporter