Nervous System Flashcards
role of nervous system
integrate info and decide on an appropriate response
sensory neurons
detect important internal and external stimuli
central nervous system (interneurons)
integrate information in its current context and with recent history to produce the most appropriate output
majority of cells in nervous system
interneurons
morot neurons
carry the output of the central nervous system to the effector cells that produce the appropriate response
neurons
the functional unit of the nervous system
receive and transmit info
transduction
conversion of energy from one form to another
GLIA
supporting cells in the nervous system that fulfill a variety of important rolls
roles of GLIA
structural support maintenance of ionic compositions remove extra chemicals insulate neurons electrically formation of blood brain barrier provide a path for developing neurons secretion of compounds for neuronal maintenance participate in flow in the nervous system
membrane potential
language of neurons
potential difference across their plasma membrane
Vm
equilibrium
electrical gradient and concentrating gradient balance out
two factors affect movement of ions
concentration gradient
charge
synaptic transmission
cell to cell communications
electrical synapses ( gap junctions)
provide a direct connection between cells.
very fast, reliable, limited to flexibility
formed by proteins called connexons
excitatory (depolarizing) na+ ca2+ channels
moves cell closer to threshold
inhibitory ( hyperpolarizing) k+ cl- cahnnels
moves cell further from threshold
summation
postsynaptic neurons sum up all their inputs in both time and space…
synaptic integration
excitatory
depolarizing
inhibits
hyperpolarization
indirect synaptic transmission
activation of 2nd messenger pathways
neurotransmitter binds to and activates a receptor that is not directly coupled with an ion channel
AMPA
cation selective channel (Na, K)
NMDA
permeable to Na, K, and Ca
active only when both glutamate is bound and the cell is depolarized
depolarization
due to increase in activity
activation
mV becoming more positive
hyperpolarization
decrease in activity
inhibition
mV becoming less positive