Nervous System Flashcards
Two organizations of the nervous system
Central Nervous System (CNS)
Peripheral Nervous System (PNS)
What consists of the CNS?
- Brain
- Spinal Cord
What consists of the PNS?
-all of the nervous tissue outside of the CNS
Functions of the NS
- Sensory
- Integrative
- Motor
Detection and input
Sensory
Processing/storing/analyzing info
Integrative
Output
Motor
What is nervous tissue designed for?
Communication
Types of cells of NS
- Neuroglia
2. Neurons
Function of neuroglia
Support, Nourish, Protection
3 parts of nerve cells
- Dendrite
- Cell Body
- Axon
Structure, Function, Receptor Sites of Dendrites
Structure: multiple/single extensions off cell body
Function: input portion of the neuron
Receptor Sites: contains lots for receiving chemical messages from other cells
A.k.as for Cell Body
Soma, Perikaryon
Structure, Function Of the Soma
Structure: contains the nucleus and other organelles
Function: cell proccesses
Structure, Function of Axons
Structure: a thin cylindrical process off the cell body
Function: output portion of the neuron
What is the presynaptic terminal?
The end of the axon that divides into many fine processes
A.k.a Axon Terminal
What is the synaptic end bulb?
The swollen ends of some axon terminals.
What is myelin?
Multilayered lipid and protein covering that speeds up signal conduction (action potential)
What is a stimulus?
Any change in the internal/external environment that is strong enough to stimulate an AP
What is an action potential?
An electrical signal that travels along the cell membrane of a neuron
Responding to a stimulus and converting it into an action potential
Electrical Excitability
3 Structural Classifications of Neurons
- Multipolar
- Bipolar
- Unipolar
Structurally, what classifies a neuron?
Classified according to number of processes extending from the cell body
Several dendrites and one axon
Multipolar
One main dendrite and one axon
Bipolar
Peripheral axon has sensory receptors and the central axon has axon terminals
Unipolar
Where would you find multipolar neurons?
Brain, Spinal Cord (CNS), and all Motor Neurons
Where would you find bipolar neurons?
Retina, Ear
Where would you find unipolar neurons?
All sensory neurons
3 Functional Classifications of Neurons
- Sensory Neurons
- Motor Neurons
- Interneurons
A.k.a Sensory Neuron
Afferent Neurons
A.k.a Motor Neuron
Efferent Neurons
A.k.a Interneurons
Association Neurons
Sensory neurons are mostly what structural classification?
Unipolar
Where are the sensory receptors for sensory neurons?
Either at dendritic end or just after sensory receptors that are separate cells
What happens once a sensory neuron is activated by a stimulus?
The AP forms and propagates along the axon and is carried into the CNS via afferent neurons
Must travel together in spinal and cranial nerves
Sensory Neurons
What structural classification belongs to motor neurons?
Multipolar
What happens to the AP in motor neurons?
Propagates away from the CNS to effectors via efferent neurons
What are effectors?
The cells and organs
Where are interneurons located?
Primarily in the CNS between the sensory and motor neurons
What is the interneuron’s role?
Integrate/process information from the sensory neurons. If a motor response is required, specifics of that response is formulated and relevant motor neurons are activated.
What structural classification are interneurons?
Multipolar
The site of communication between two neurons (or b/w a neuron and another type of cell)
Synapse
2 Types of synapses
- Electrical
2. Chemical
Which synapse is faster and not as common?
Electrical
In electrical synapses, APs conduct directly between _______ through ______.
Plasma membranes of adjacent cells through gap junctions
What do electrical synapses allow for?
Synchronization of function
Neuron sending the signal
Pre-synaptic neuron
Neuron receiving the signal
Post-synaptic neuron
The space between the communicating neurons
Synaptic Cleft
Chemical released by the pre-synaptic neuron to affect the post-synaptic neuron or effector
Neurotransmitter (NT)
What should you think of when it comes to neurotransmitters?
“Lock and Key” because NT binding receptors are specific to the NT released
What happens when the AP reaches the end of the pre-synaptic neuron?
- Neurotransmitter releases
- NT diffuses across the synaptic cleft
- NT binds to post-synaptic cleft
When is the continuation of the AP more likely?
If NT is excititory
When is the continuation of the AP less likely?
If NT is inhibitory
Common Neurotransmitters (4)
- Acetylcholine (ACh)
- Gamma-aminobutyric Acid (GABA)
- Dopamine
- Serotonin
PNS/CNS excitatory at neuromuscular junction (NMJ)
Acetylcholine (ACh)
CNS, inhibitory
Gamma-aminobutyric Acid (GABA)
Excitatory or inhibitory depending on receptor, emotional response, addictive behaviour, skeletal muscle tone
Dopamine
Excitatory or inhibitory depending on receptor, sensory perception, temperature regulation, mood, sleep, appetite
Serotonin
In cases of injury/disease, what does neuroglia do?
Multiplies to fill the spaces formerly occupied by neurons
Neuroglia in the CNS (4)
- Astrocytes
- Oligodendrocytes
- Microglia
- Ependymal Cells
Helps form the blood-brain barrier and provides nutrients to neurons
Astrocytes
What is the blood-brain barrier? Structural components?
- Specialized barrier that prevents passage of materials from the blood and the brain
- Protects the brain from harmful substances
- Thick basement membrane, tight junctions
Form/maintain the myelin sheath of CNS neurons
Oligodendrocytes