nervous and intro to genetics Flashcards

1
Q

Making connections to the world from the body (reacting to stimuli) this is called

A

irritability

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2
Q

Organizing and storing information is

A

conductivity

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3
Q

Produce movements

A

effectors

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4
Q

CNS make up

A

brain, spinal cord, neurons cluster in nuclei, axons are bundles in tracts/fasciculi

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5
Q

PNS

A

cranial nerves, spinal nerves, carries messages to and from the CNS
neurons cluster in ganglia, axons are bundles as nerves

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6
Q

Glial cells are ____ cells

A

support cells

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7
Q

Grey matter is composed of

A

cell bodies and dendrites

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8
Q

white matter is composed of

A

axons

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9
Q

Soma =
Dendrites=
axon=

A

Soma= cell bosy, responsible for reception and integration of information
neurons= processes that recieve information
axon= conducts information away from the cell via and action potential or nerve impulse

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10
Q

Multipolar:
bipolar:
pseudounipolar:

A

multipolar: many dendrites, one axon (motor)
bipolar: one dendrite, one axon (special senses)
pseudounipolar: one nerve process (sensory ganglia of spinal and cranial nerves)

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11
Q

PNS neurons cluster within ____

A

ganglia.

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12
Q

An area where gray matter forms a layered surface that covers some part of the CNS is referred to as a _____

A

cortex

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13
Q

The ridges/ folds are called ____
The grooves between gyri are called _____

A

Ridges: gyri
grooves: sulcus

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14
Q

Where do our motor/efferent neurons exist?

A

the ventral/anterior horn

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15
Q

Simply put, what is a peripheral nerve?

A

simply a bundle of axons that are traveling together

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16
Q

Endoneurium:
perineurium:
epineurium:

A

Endoneurium: connective tissue that surrounds and holds together axons into bundles (called fasicles)
perinerium: Layer that surrounds each fasicle
epineurium: all fasciles are bound together and surrounded by

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17
Q

T/F Axons converge and diverge in the fascicles of a nerve

A

T. fasicles are not completely independent

18
Q

Simply put, what are cranial nerves

A

cranial nerves are nerves that emerge from the brainstem
there are 12 cranial nerves

19
Q

The ventral root is (efferent or afferent) only
the dorsal root is (efferent or afferent) only

A

ventral = efferent
dorsal = afferent
BUT both dorsal and ventral rami typically contain both afferent and efferent axons

20
Q

Afferent means

A

neurons that carry information FROM sensory receptors found all over the body towards the CNS

21
Q

Efferent means

A

neurons carry motor information away from the CNS to the muscles and glands of the body in order to initiate an action

22
Q

T/F a peripheral nerve cannot be made up of motor and sensory axons from more than one spinal nerve.

A

FALSE. fascicles split apart and join together as the nerves course through the body, this also ensures that a peripheral nerve is made up of motor and sensory axons from more than one spinal nerve.

23
Q

All of our blood to our brain will be derived from two specific arteries

A
  1. the internal carotid = anterior circulation
  2. Vertebral artery = posterior circulation
24
Q

Lateral aspect of the cerebrum is supplied by the

A

middle cerebral artery

25
Q

The medial aspect is supplied by the

A

both anterior cerebral artery and posterior artery

26
Q

Posterior intercostal aa that branch from the aorta and then divide into segmental spinal arteries. These then give off_______ aa that supply the _________ and the roots that form it.

A

these give off RADICULAR AA that supply the spinal nerve and the roots that form the spinal nerve. The radicular arteries will also contribute to the anterior spinal a.

27
Q

An aneursym

A

weakening of the artery wall

28
Q

occluded vessels

A

development of a plaque within the lumen of a vessel

29
Q

aterioneous malformations

A

developmental abnormalities where there is an abnormal connection between arteries and veins

30
Q

Allosomal vs autosomal

A

Autosomal = on a chromosome that is not a sex chromosome
Allosomal= on a sex chromosome

31
Q

What is the simplest form of genetic polymorphism?

A

Single nucleotide polymorphism= single base (point) mutation

32
Q

T/F a SNP in a coding region can be synonymous

A

yes. it does not change the amino acid that is produced

33
Q

A SNP in a coding region can be non-synonymous. What is the result of this

A
  1. results in missense or nonsense mutations
    missense= incorrect amino acid, produces malfunctioning protein
    nonsense= incorrect sequence causes shortening of protein IT STOPS
34
Q

pleiotropy

A

multiple traits are effected by one gene.

35
Q

polygenic inheritance

A

multiple genes affect one trait

36
Q

What is X inactivation

A

one copy of X chromosome in each cell is silenced. this leads to mosaic phenotypes in heterozygotes

37
Q

epistasis

A

interaction between genes
alleles at one locus are blocked by the presence of a specific allele at another locus

38
Q

Linkage
Recombination (meiosis) allows swapping of ______ to increase variation
-genes close to each other on the same chromosome are ________ to be inherited together

A

swapping of genes
are much more likely to be inherited together

39
Q

What is linkage disequilibrium

A

nonrandom association of alleles of different loci
basically measures the degree to which alleles at two loci are associated

40
Q

penetrance

A

is the liklihood that you will develop the disease given that you have the risk allele

41
Q

Expressivity

A

refers to the severity of the disease if the risk allele is present
example: having a cleft lip