NERVE PHYSIO - Local Current Flow Flashcards

0
Q

Local current flow is the..

A

Net movt of positive charge

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1
Q

Wave of depolarization across the membrane

A

Local current flow

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2
Q

Each action potential triggers a new one at the adjacent area of the membrane by

A

Local current flow

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3
Q

Flow of positive charges

A

Active area or active point

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4
Q

No stimulus applied

A

Inactive point

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5
Q

Current of positive charge moves from INACTIVE point to ACTIVE point

A

Extracellular fluid

EIA

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6
Q

Current of positive charge will move from

ACTIVATED -> INACTIVE POINT

A

Intracellular

IAI

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7
Q

Characteristic of nerve impulse

A

Self propagating
Decrement less
Bidirectional
Velocity of the impulse

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8
Q

Always have to reach its final destination

A

Self propagating

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9
Q

Magnitude of a potential will not change as it moves across the membrane

A

Decrement less

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10
Q

Velocity of impulse will vary depending on the

A

Diameter of the fiber

Whether the nerve fiber is myelinated or unmyelinated

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11
Q

Difference of active area or inactive area

A

Active point is the Flow of positive charges

while inactive point, there is no stimulus applied.

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12
Q

Ecf vs icf

A

Ecf- current of + charge moves from inactive to active

Icf-current of + charge moves from active to inactive

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13
Q

Characteristics of nerve impulse

A
Self propagating
Decrementless
Bidirectional
Velocity of impulse
All or none principle
Exhibits refractory period
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14
Q

What is self propagating?

A

Always have to reach its final destination

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15
Q

Decrementless?

A

Magnitude of a potential will not change as it moves across the membrane

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16
Q

Why is conduction in myelinated fiber faster than unmyelinated?

A

In myelin sheath, there is an uninsulated area which is the node of ranvier. It causes saltatory conduction wc is jumping from one node of ranvier to another

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17
Q

What is an impulse

A

It is an electric current aka action potential

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18
Q

Diff types of nerve fibers

A

A fiber
B fiber
C fiber

19
Q

A fiber

A

Large myelinated

Conduct impulse at greatest speed

20
Q

B fiber

A

Smaller myelinated

Slower conduction

21
Q

C fiber

A

Smallest unmyelinated

Slowest conduction

22
Q

What is multiple sclerosis

A

It is a degenerative disease in wc there is an impaired nerve fiber

23
Q

What is all or none principle

A

Response of a single nerve fiber is always maximized for the existing conditions at that time
It will either respond or not respond at all
There is accurate transmission of impulse

24
Q

What is refractory period?

A

Aka as rest period

Nerve is unexcitable between the time of depolarization and upper 1/3 of repolarization

25
Q

2 types of refractory period

A

Absolute ref period

Relative ref period

26
Q

Absolute refractory?

A

After a nerve has conducted an impulse, cannot immediately conduct a 2nd impulse at the 2nd time.

27
Q

Relative refractory?

A

2nd stronger stimulus given, reaction will occur

28
Q

What is a synapse?

A

A site of interaction between 2 neurons or between a neuron and effector cells

29
Q

Effector cells?

A

Muscle cells or glands

30
Q

2 types of synapse

A

Chemical synapse

Electrical synapse

31
Q

What kind of synapse is nmj

A

Chemical synapse

32
Q

Electrical synapse is between

A

Neuron to neuron

33
Q

Chemical synapse is between

A

Muscle to nerve

No anatomical continuity

34
Q

Presynaptic neuron

A

Moves the impulse toward the synapse

35
Q

Postsynaptic neuron

A

Moves the impulse away from the synapse

36
Q

Contain transmitter sybs that either excites or inhibits postsynap neuron

A

Transmitter vesicles

37
Q

Provide atp

A

Mitochondria

38
Q

Small swelling on an axon branch lying very close to the dendrite of another neuron

A

Axon bulb

39
Q

Expanded tip of axon facing sarcolemma

Contain alot of mito and neurotransmitters

A

Synaptic knob

40
Q

Cell membrane of muscle tissue

A

Sarcolemma

41
Q

Space in bet

A

Synaptic cleft

42
Q

Enzyme win synaptic cleft that breaks down acetylcholine into cholic acid and acetyl

A

Acetylcholinesterase

43
Q

Impulse transmission across the synapse

A

Synthesis and storage of ach
Release of transmitter substance via exocytosis
Binding of tranmitter with a receptor forming transmitter receptor complex
End plate potential causing action potential
Dissipation of the transmitter substance

44
Q

Characteristics of impulse conduction across the synapse

A

Operates in one direction only
Conduction is slow
Synapse is vulnerable to drug or toxin
Susceptible to fatigue