Nerve conduction - Synapse (3) Flashcards

1
Q

The type of affect NT has on postsynaptic membrane is determined by what?

A

The type of ion channels it opens

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2
Q
  1. The type of affect nt has on post sy membrane is determined by the type of ion channels it opens: Na+
A
  • Na+ enters neuron and produces excitatory post synaptic potential (depolarization)
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3
Q
  1. The type of affect nt has on post sy membrane is determined by the type of ion channels it opens: K+
A
  • K+ leaves the neuron and produces inhibitory post synaptic potential (hyperpolarization)
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4
Q
  1. The type of affect nt has on post sy membrane is determined by the type of ion channels it opens: Cl-
A

a. if neuron is at rest diffusion and electrostatic forces are balanced and there is no Cl- movement and thus has no affect
b. If neuron is firing, the outside of membrane will be negative and electrostatic force will cause Cl- to enter neuron and it will “neutralize” the EPSP by returning the membrane to resting potential and slow the rate of firing

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5
Q
  1. The type of affect nt has on post sy membrane is determined by the type of ion channels it opens: Ca+EPSP
A

a. causes release of ts in terminal button
b. binds with and activates enzymes that are involved in biochemical and structural changes in neurons important for processes such as learning

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6
Q

What happens to postsynaptic potentials briefly after release?

A

TERMINATION!

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7
Q

What is the most common form of NT deactivation?

A
  • Reuptake most common form of nt deactivation – membrane contains transporter molecules that remove nt from cleft into cytoplasm
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8
Q

How is acetylcholine (ach) deactivated?

A
  • Ach is deactivated by enzyme present in cleft called acetylcholinesterase which divides Ach into constituent molecules
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