Nerve conduction - Synapse (3) Flashcards
The type of affect NT has on postsynaptic membrane is determined by what?
The type of ion channels it opens
- The type of affect nt has on post sy membrane is determined by the type of ion channels it opens: Na+
- Na+ enters neuron and produces excitatory post synaptic potential (depolarization)
- The type of affect nt has on post sy membrane is determined by the type of ion channels it opens: K+
- K+ leaves the neuron and produces inhibitory post synaptic potential (hyperpolarization)
- The type of affect nt has on post sy membrane is determined by the type of ion channels it opens: Cl-
a. if neuron is at rest diffusion and electrostatic forces are balanced and there is no Cl- movement and thus has no affect
b. If neuron is firing, the outside of membrane will be negative and electrostatic force will cause Cl- to enter neuron and it will “neutralize” the EPSP by returning the membrane to resting potential and slow the rate of firing
- The type of affect nt has on post sy membrane is determined by the type of ion channels it opens: Ca+EPSP
a. causes release of ts in terminal button
b. binds with and activates enzymes that are involved in biochemical and structural changes in neurons important for processes such as learning
What happens to postsynaptic potentials briefly after release?
TERMINATION!
What is the most common form of NT deactivation?
- Reuptake most common form of nt deactivation – membrane contains transporter molecules that remove nt from cleft into cytoplasm
How is acetylcholine (ach) deactivated?
- Ach is deactivated by enzyme present in cleft called acetylcholinesterase which divides Ach into constituent molecules