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Renal > Nephrotic syndrome/non-proliferative > Flashcards

Nephrotic syndrome/non-proliferative Flashcards

1
Q

Symptoms of Nephrotic

A 
LEAP
Lipids increased (hypercholesterolaemia)
Edema
Azotemia
Proteinuria +++ >3.5g/day
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2
Q

Minimal change disease

A

Kids
LM - no changes, EM - loss of podocyte foot processes
Prednisolone

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3
Q

FSGS

A 
Most common cause of nephrotic in adults
Caused by idiopathic, drugs, viral infections
LM - focal segmental sclerosis
Pred and cyclophosphamide
50% progress to CRF in 10 years
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4
Q

Membranous GN

A

Caused by idiopathic, NSAIDs, hep B, malignancy
Immune deposits of Ag in subepithelium, IgG and C3, GBM spikes
Cyclophosphamide
Rule of 1/3

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Renal (3 decks)

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