Nephritic syndrome/proliferative Flashcards

1
Q

Nephritic Symptoms/Signs

A
PHARAOH
Proteinuria (<3.5)
Haematuria
Azotemia
RBC casts
And...
Oligouria
Hypertension
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2
Q

IgA

A
Most common
Usually a few days after an URTI
Associated with Henoch-Schonlein purpura in kids
Diffuse mesangial IgA deposition
Prednisolone and cyclophosphamide
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3
Q

Post-infectious GN

A

Kids
Following strep-A infection of skin or pharyngitis (1-3 weeks)
Increased C3 and IgG
May need dialysis

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4
Q

Membrano-proliferative GN

A

Caused by idiopathic, Hep B/C, HIV
“Tram tracks”
Prednisolone, cyclophosphamide

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5
Q

Anti-GBM

A

Goodpasture’s
Linear IgG deposits
Pred, cyclophosphamide, plasmapheresis

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6
Q

Pauci immune

A

Wegner’s, Churg-Strauss
Vasculitis necrotising inflammation
Pred, cyclophosphamide, ribuximab
c-ANCA (Wegner’s), p-ANCA (Churg-Strauss)

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