Nephrotic syndrome

Question 1

how does glomerulonephritis differ from nephrotic syndrome?

Answer 1

glomerulo= lose protein

nephro= losing an ass load of protein (has bigger holes for protein to come out of) more than glomerulo

Question 2

explain the patho of nephrotic syndrome.

Answer 2

inflammatory response in glomerulus= cause big holes to form= an ass load of protein start leaking from the big holes= causes your body to lose A LOT of protein and you become hypo-album (and we know protein is important for fluid maitnenace in the vascular space)= low protein causes fluid shift to the tissues and you get anasarca.

Question 3

Since all of the fluid is now in the tissues, what has happened to the circulating blood volume?

Answer 3

decreased

Question 4

since we now have low circulating blood volume, what do the kidneys do?

Answer 4

they secrete alodosterone causing you to retain sodium and water.

Question 5

why do we want this patient on bedrest?

Answer 5

bed rest induces diuresis

Question 6

why would this patient go on prednisone?

Answer 6

-decrease inflammation and it also shrinks the holes so protein cannot get out

Question 7

what is the main complication of prednisone or other steroids?

Answer 7

immunosupression

Question 8

what are we gonna do with the protein in the diet?

Answer 8

increase it

Question 9

the common rule with protein and kidney disease is__

Answer 9

to limit protein with kidney problems except with nephrotic syndrome

Question 10

A lasix and albumin infusion… how would this help?

Answer 10

albumin= pull fluid back into the vascular space

lasix= without it, they’d get hypervolemic