nephrogenic systemic fibrosis/dermopathy (NSF/NSD) Flashcards
1
Q
epidemiology
A
5th decade
2
Q
what is the typical scenario for these patients?
A
recent IV gadolinium exposure in a patient with AKI or CKD. often 2-4 weeks after IV gad exposure
3
Q
clinical findings
A
symmetric, painless, hyPERpigmented, indurated plaques on extremities>trunk
4
Q
eye finding **
A
scleral plaque (white-yellow plaque on eye in patients < 45 yo**)
5
Q
dermpath
A
similar to scleromyxedema but extends into deep fascia
6
Q
treatment
A
- treat underlying kidney disease
- physical therapy to prevent joint contractures
- tends to be refractory to oral steroids and/or immunosuppressive agents
