Nephro

Question 1

Features of nephrotic syndrome

Answer 1

1. Massive proteinuria
2. Edema
3. HypERlipidemia
4. HyPOalbuminemia

Question 2

Etiology or nephrotic syndrome
A (5)
B (3)
C _

Answer 2

A. Primary
1. Minimal change disease
2. Membranous nephropathy
3. FSGN
4. C3 glomerulopathy
5. Membranoproliferstive GN

B. Secondary
1. Infection
2. Malignancy
3. Systemic dse (SLE HSP etc)

C. hereditary

Question 3

Nephrotic syndrome that is most common cause of esrd in adolescents

Answer 3

FSGN

Question 4

Most common cause of childhood nephrotic syndrome

Answer 4

Minimal Change nephrotic syndrome

Question 5

Differential diagnosis in children presenting edema

Answer 5

1. Protein losing enteropathy
2. Hepatic failure
3. Heart failure
4. AGN/CGN
5. Protein malnutrition
6. Allergy

Question 6

Diagnostics/ evaluation to rule out secondary forms of nephrotic syndrome in children

Answer 6

1. C3 level
2. ANA
3. DsDNA
4. Hepa B and C, HIV in high risk population
5. Renal biopsy if >13 y/o

Question 7

attainment of remission within initial 4-wk steroid therapy

Answer 7

Steroid responder

Question 8

Urine prot/crea ratio <0.2 or <1+ protein on dipstick testing for 3 consecutive days usually within 2-3wks treatment

In short absence of proteinuria

Answer 8

Remission

Question 9

Urine prot/crea ration of >2 or 2+ above in dipstick for 3 consecutive days

Answer 9

Relapse

Question 10

> =2 relapse in 6mos after initial therapy or 4 relapses in a 12 month period

Answer 10

Frequent relapse