Neoplasia: oncogenesis & pre-malignancy Flashcards

1
Q

How do cells accumulate hallmarks of cancer by which 2 mechanisms

A

Either

  • activation of oncogenes (accelerator of cell cycle)
  • Inactivation of tumour suppressor genes (brakes of cell cycle)
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2
Q

What is an oncogene

A

Dysregulated proto-oncogene causing cell to grow independently

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3
Q

What is a photo-oncogene

A

A normal gene whose product promotes cell growth

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