Neoplasia: oncogenesis & pre-malignancy Flashcards
1
Q
How do cells accumulate hallmarks of cancer by which 2 mechanisms
A
Either
- activation of oncogenes (accelerator of cell cycle)
- Inactivation of tumour suppressor genes (brakes of cell cycle)
2
Q
What is an oncogene
A
Dysregulated proto-oncogene causing cell to grow independently
3
Q
What is a photo-oncogene
A
A normal gene whose product promotes cell growth