Neonatology Flashcards
Features of Pierre Robin sequence
Micrognathia, glossoptosis, midline cleft of soft palate
Which trimester infection causes congenital rubella?
First
What are the most common features of congenital rubella?
Congenital heart disease
Cataracts
Deafness
Which congenital infection syndrome overlaps with rubella?
CMV
What are the features of congenital toxoplasmosis?
Retinopathy
Cerebral calcification
Hydrocephalus
What are the features of congenital listeria infection?
Spontaneous abortion Preterm delivery Fetal/neonatal sepsis Meconium stained liquor Widespread rash Pneumonia Meningitis
What are the features of congenital CMV infection?
IUGR Prematurity Hepatosplenomegaly Thrombocytopenia Anaemia Jaundice, often prolonged Pneumonitis Microcephaly Intracranial calcification Choroidoretinitis Osteitis Long term neurodevelopmental sequelae are common
What are the features of foetal alcohol syndrome?
SGA Dysmorphic face Microcephaly Intellectual impairment Congenital heart disease Postnatal growth failure
What are the dysmorphic features of foetal alcohol syndrome?
Mid face hypoplasia Short palpebral fissures Epicanthic folds Flat nasal bridge (resulting in small upturned nose) Long philtrum Thin upper lip Micrognathia Ear abnormalities
What is retinopathy of prematurity?
Vascular proliferation secondary to retinal vasoconstriction which can progress to fibrosis and scarring
Which stage of ROP needs treatment and with what?
Stage 3+, with laser or cryotherapy
What is the limit of viability?
22 weeks if favourable features
23 otherwise
What are the favourable features for a 22 weeker?
Female
Singleton
Good dopplers and growth
Towards end of week
What is the survival for a 22 weeker?
3 in 10 survive, 1 in 3 with severe disability
What is the survival for a 23 weeker?
4 in 10 survive, 1 in 4 with severe disability
