Neonates Flashcards
Chronic perinatal infections
CHEAP TORCHES Chicken pox/shingles Hep B Ebstein-Barr virus AIDS (HIV) Parvovirus B19 (erythema infectious) Toxoplasmosis Other Rubella virus Cytomegalovirus/Coxsakievirus Herpes simples virus Every STI Syphillis
Bacteria causing neonatal sepsis
common= GBS
less common - E.COli, Listeria, Klebsiella, Enterobacter
Signs of sepsis neonate
- Tachycardia
- Febrile (>38) temp instability
- hypotensive
- Tachyponea. respiratory distress
- unexplained need for resusc
- Poor peripheral perfusion
- Apneoic episodes
- lethargy
- seizures
- poor feeding
- metabolic/respiratory acidosis
- Hypoglycemic
APGAR
OUT OF 10
appearance, PR, grimace, activity, Resp effort
low score: <7 needs med attention
Antibiotics for sepsis (empirical)
penicillin 60mg/kg/dose BD or ampicillin 50mg/kg/dose BD +
>30wk = gentamicin 2.5mg/kg daily ; <30 = 2.5mg/kg 36hrs for 3days. (check levels after 2nd day)
duration Rx -
- consult w paediatrician, ID
- -ve BC: discontinue after 36hrs
- sepsis proven, suspected cont for 5-7days
General D/C adivise to new parents
1) Personal health record (RED BOOK)
2) Child health info booklet
3) Feeding
4) Safe sleeping
5) Injury prevention, reducing home hazards
6) Vaccinations
7) Parent/carer pertussis vaccination
8) Role of GP
9) Role of child health nurse/commu midwife/healthcare worker
10) Repeat neonatal check 7 days w GP
Resusc steps:
- Dry, stimulate and open airway
- Positive pressure ventilation (+ sats monitoring)
- Ensure open airway / reduce leaks / consider increasing pressure and oxygen
- Start chest compressions
- Consider intubation
- Venous access, adrenaline
- Consider volume expansion
Neonatal Hypoglycemia - maternal causes
- DM, GDM
- Medications - sodium valproate, citalopram, oral hypoglycemics, beta-blockers
- Intrapartum glucose
Neonatal hypoglycaemia - neonate causes
Prematurity IUGR Macrosomia Hypoxic ischemic injury Respiratory distress Sepsis Hypothermia Congenital cardiac disease Metabolic disease Rh haemolytic disease Inadequate feeding Endo causes: hypopituitarism, hyperinsulinism
Fluid order for hypoglycaemic, unwell baby:
IV 10% dextrose at 60 ml/kg/day (divide w 24 to get hrly rate)
recheck after 30 minutes and adjust IV dextrose as required to achieve BGL ≥ 2.6.
Prematurity - short term risks
- Respiratory distress
- Intraventricular hemorrhoage
- Jaundice of prematurity
- Inability to suck feed
- Apnoea of prematurity
- Hypoglycemia
- Hypothermia
- Retinopathy of prematurity
- PDA
- Necrotising enterocolitis
- Increased risk of infection
Prematurity - long term risks
- Frequent hospitalizations (eg resp infections)
- Hearing impairement
- Visual impairement
- Imparied cognitive skils
- Motor deficits including fine or gross motor delay and cerebral palsy
- Behvioural and psychological probs
- Herniae
- Growth impairement
- Potential impacts on adult health such as – insulin resistance, HTN, vascular changes
- Lower reproduction rates.
respi distress - common causes
TTN (retained fetal lung fluid
RDS (hyaline membrane dis)
Sepsis
Respi distress - not to miss
RDS (prematurity) Sepsis (RF GBS infection) Isolated pneumothorax (resusc) Meconium aspiration syndrome Pneumonia CHD Congenital lung malformation
TTN
- retained fetal lung fluid
- parenchymal lung disorder of pulmonary oedema resulting fem delayed absorption/clearance of fetal alveolar lung fluid.
RF: - late preterm 34-37wk
- c/sec
- SGA/LGA
- Maternal DM
- Maternal asthma
onset frm birth –>2hrs
lasts 12-24hrs
spontaneous resolution
rarely req supplemental oxygen or mech ventilation