Neonates Flashcards
Chronic perinatal infections
CHEAP TORCHES Chicken pox/shingles Hep B Ebstein-Barr virus AIDS (HIV) Parvovirus B19 (erythema infectious) Toxoplasmosis Other Rubella virus Cytomegalovirus/Coxsakievirus Herpes simples virus Every STI Syphillis
Bacteria causing neonatal sepsis
common= GBS
less common - E.COli, Listeria, Klebsiella, Enterobacter
Signs of sepsis neonate
- Tachycardia
- Febrile (>38) temp instability
- hypotensive
- Tachyponea. respiratory distress
- unexplained need for resusc
- Poor peripheral perfusion
- Apneoic episodes
- lethargy
- seizures
- poor feeding
- metabolic/respiratory acidosis
- Hypoglycemic
APGAR
OUT OF 10
appearance, PR, grimace, activity, Resp effort
low score: <7 needs med attention
Antibiotics for sepsis (empirical)
penicillin 60mg/kg/dose BD or ampicillin 50mg/kg/dose BD +
>30wk = gentamicin 2.5mg/kg daily ; <30 = 2.5mg/kg 36hrs for 3days. (check levels after 2nd day)
duration Rx -
- consult w paediatrician, ID
- -ve BC: discontinue after 36hrs
- sepsis proven, suspected cont for 5-7days
General D/C adivise to new parents
1) Personal health record (RED BOOK)
2) Child health info booklet
3) Feeding
4) Safe sleeping
5) Injury prevention, reducing home hazards
6) Vaccinations
7) Parent/carer pertussis vaccination
8) Role of GP
9) Role of child health nurse/commu midwife/healthcare worker
10) Repeat neonatal check 7 days w GP
Resusc steps:
- Dry, stimulate and open airway
- Positive pressure ventilation (+ sats monitoring)
- Ensure open airway / reduce leaks / consider increasing pressure and oxygen
- Start chest compressions
- Consider intubation
- Venous access, adrenaline
- Consider volume expansion
Neonatal Hypoglycemia - maternal causes
- DM, GDM
- Medications - sodium valproate, citalopram, oral hypoglycemics, beta-blockers
- Intrapartum glucose
Neonatal hypoglycaemia - neonate causes
Prematurity IUGR Macrosomia Hypoxic ischemic injury Respiratory distress Sepsis Hypothermia Congenital cardiac disease Metabolic disease Rh haemolytic disease Inadequate feeding Endo causes: hypopituitarism, hyperinsulinism
Fluid order for hypoglycaemic, unwell baby:
IV 10% dextrose at 60 ml/kg/day (divide w 24 to get hrly rate)
recheck after 30 minutes and adjust IV dextrose as required to achieve BGL ≥ 2.6.
Prematurity - short term risks
- Respiratory distress
- Intraventricular hemorrhoage
- Jaundice of prematurity
- Inability to suck feed
- Apnoea of prematurity
- Hypoglycemia
- Hypothermia
- Retinopathy of prematurity
- PDA
- Necrotising enterocolitis
- Increased risk of infection
Prematurity - long term risks
- Frequent hospitalizations (eg resp infections)
- Hearing impairement
- Visual impairement
- Imparied cognitive skils
- Motor deficits including fine or gross motor delay and cerebral palsy
- Behvioural and psychological probs
- Herniae
- Growth impairement
- Potential impacts on adult health such as – insulin resistance, HTN, vascular changes
- Lower reproduction rates.
respi distress - common causes
TTN (retained fetal lung fluid
RDS (hyaline membrane dis)
Sepsis
Respi distress - not to miss
RDS (prematurity) Sepsis (RF GBS infection) Isolated pneumothorax (resusc) Meconium aspiration syndrome Pneumonia CHD Congenital lung malformation
TTN
- retained fetal lung fluid
- parenchymal lung disorder of pulmonary oedema resulting fem delayed absorption/clearance of fetal alveolar lung fluid.
RF: - late preterm 34-37wk
- c/sec
- SGA/LGA
- Maternal DM
- Maternal asthma
onset frm birth –>2hrs
lasts 12-24hrs
spontaneous resolution
rarely req supplemental oxygen or mech ventilation
RDS (hyaline membrane dis)
- reduced amt of surfactant
- preterm neonates
- worsens if not Rx
- S/S - tachypnoea, nasal flaring, grunting, recession, cyanosis, BS (may be reduced)
PPH
- abnorm persistence of high pulmonary vascular resistance
- -> deoxygenated blood shunted R->L through foramen oval and ductus arteriosus –> hypoxia
- cause - underdevelopment of pulmonary vasculature (other asso congen structural abnorm e.g. congenital diaphragmatic hernia) or maladaption (w chronic inter stress –> mec aspiration
- term/post-term
- tachypnoea & cyanosis
- may be systolic murmur of tricuspid insuff
- asso w: sepsis, hypoxia-ischemia, MAS, congenital diaphragmatic hernia
- little improvement in sats w oxygen.
Congenital cardiac disease
- mild respi distress and tachycardia
- lung function, oxygenation and CXR doesn’t improve w resp support and surfactant.
Pneumothorax
- air leak more common in neonatal period than any other. RF: - prematurity - mechanical ventilation - MAS - RDS - TTN - pulmonary hypoplasia - pneumonia S/S - asymmetrical chest expansion - affected side - larger, reduced air entry - if large - bradycardia, hypotension, hypoxia (related to reduced CO)
MAS
- RF: Post term or SGA w mec liquor, asphyxiation
- Resp distress IMMEDIATELY after birth
- Mec –> infection, interferes w surfactant, chemical irritation
- Signs - barrel shaped chest, crackles and wheeze
- Complications = pneumothorax, PPHTN
RF (5) Early onset neonatal sepsis
- preterm labour 18hrs
- maternal temp >38C
- GBS colonisation current prey
- previous child w EOGBSD
Signs of Early onset neonatal sepsis
- tachypnoea, respiratory distress, apnoeic episodes
- tachycardia
- fever, temp instability
- hypotension, poor perish perfusion
- unexpected need for resusc
- lethargy
- seizures
- poor feedings
- abdo distention
- hypoglycaemia
- metabolic/respi acidosis
Mx - respi distress poss sepsis (6)
- oxygen supp - 92-96%
- CXR
- IV access - FBC, BC,
- IV antibios
- IV fluids 60ml/kg/day 10% dextrose
- transfer - SCN further mx and obs.
Explain to parents - re baby going to SCN
- Why going there.
- What will be done (lines)
- Parental involvement
- how long baby will be there
- any questions
info b4 d/c newborn - baby
GA - term? age - hrs blood group, rh, DAT/coombs (cord blood) respiratory distress resusc? agars? NICU? feeding birth weight passed mec/urine hep b and vit k given
info b4 d/c newborn - mum
age GsPs problems during this pregnancy serology delivery - mode, complications when ROMd, antibios? Maternal fever GA (term/pre/post) medical conditions/medications blood group, rh status GBS status