Neonates

Question 1

Risks for neonates after parturition

Answer 1

Obtaining oxygen from lungs rather than placenta
* Need surfactant
* Need to open within first few breaths
* Will have his RR initially
Poorly developed thermoregulatory mechanisms
* Will be wet
Immature renal and hepatic function
* High volume of distribution
High risk of hypovolaemia and hypocalcaemia
Immunologically mature
* Need colostrum within 6 hours

Question 2

How can neonates acquire immunity

Answer 2

Transplacental and colostral
Colostrum:
*IgG
* some IgM and IgE
* Maternal lymphocytes

Question 3

When should you vaccinate neonates?

Answer 3

During immunity gap
When maternal antibodies decline but before production of own antibodies
Can’t give too early - maternal antibodies will attack

Question 4

When should you vaccinate neonates?

Answer 4

During immunity gap
When maternal antibodies decline but before production of own antibodies
Can’t give too early - maternal antibodies will attack

Question 5

Why does Failure of passive transfer occur

Answer 5

Poor quality colostrum
Insufficient intake (quantity or time)

Question 6

What could cause poor quality colostrum?

Answer 6

○ Early lactation and colostral loss
○ Primiparous animals
○ Poor udder development
○ Mastitis
○ Lack of appropriate maternal antibodies

Question 7

Consequences of FPT

Answer 7

• GI disease
• Respiratory disease
• Joint sepsis
• Umbilical abscess
• Fading puppy syndrome
• Increased mortality
• Poor weight gain
• Increased antibiotic usage
• Increased cost
• Poor welfare

Question 8

Treatment of FPT

Answer 8

Donor colostrum within first 6 hours
Hyperimmune plasma

Question 9

SCID

Answer 9

Severe Combined Immune Deficiency