Neonate anat and phys Flashcards
How long is the neonate vs infant period?
Neonate - First month
Infant - First month to one year
Normal O2 consumption adult vs neonate?
Adult - 6mL/kg/min
Neonate - 3.5mL/kg/min
Normal alveolar ventilation adult vs neonate?
Adult - 130mL/kg/min
Neonate - 60mL/kg/min
Why do neonates desat faster than adults?
Increased VO2
Increased VA
Decreased FRC
pH, PaO2, and PaCO2 of mother at term?
pH - 7.40
PaO2 - 90
PaCO2 - 30
pH, PaO2, and PaCO2 of umbilical vein?
pH - 7.35
PaO2 - 30
PaCO2 - 40
pH, PaO2, and PaCO2 of umbilical arteries?
pH - 7.30
PaO2 - 20
PaCO2 - 50
How does pH, PaO2, and PaCO2 of the newborn change during the first 24 hours?
10 min - very acidotic (7.20) and hypoxic (PaO2 50)
1 hour- Trending up but PaO2 still 60
24 hours - Stabilizing with PaO2 at 70
How does hypoxemia effect ventilation before maturation? After?
What age is respiratory maturation?
Before - depresses ventilation
After - Stimulates ventilation
44 weeks post conception
Partial pressure of O2 on the P50 curve for adult? For neonate?
Neonate - 19
Adult - 26.5
What age is a decline in Hgb seen?
2 months (Hgb 10)
What age is Hgb F completely replaced?
6 months
Hgb at birth ?
17
Neonates receiving blood are at risk for what with potassium and calcium levels?
Risk for hyperkalemia from old blood
Hypocalcemia from citrate
Neonates receiving blood are at risk for what with glucose levels?
Hyperglycemia from dextrose in blood
Hgb level for blood being indicated vs needed?
<6 almost always transfusion
6-10 dependent on situation
NO UNIVERSAL TRIGGER
A blood volume loss of what percentage indicates a transfusion
> 15%
Dose for FFP?
10-20mL/kg
Dose for Plt?
1pack/10kg
From apheresis 5mL/kg
One pooled Plt will increase Plt by how much?
50,000
What is the transfusion trigger for a 2-month-old with severe cardiopulmonary disease
<13
What age should guidelines be followed for Plt transfusion?
4 months and older
How to calculate Hct?
Hgb X 3
EBL for premature neonate?
100 mL/kg