Neonatal Jaundice Flashcards

1
Q

How common is neonatal jaundice?

A

60% of neonates

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2
Q

What is a complication of neonatal jaundice if not managed properly?

A

Kernicterus = permanent brain damage

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3
Q

What is the management of neonatal jaundice?

A

Phototherapy

If v. severe: exchange transfusion

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4
Q

What is physiological jaundice?

A

Hyperbilirubinaemia after 24 hrs

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5
Q

What are the causes of physiological jaundice? (4)

A
  1. Shorter RBC lifespan (increase bilirubin production)
  2. hepatic immaturity (decreased bilirubin conjugation)
  3. Absence of gut flora impedes elimination of gut flora
  4. Exclusive breastfeeding
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6
Q

When should you worry about neonatal jaundice?

A

Before 24 hours

Doesn’t fade by 14 days (term) or 21 days (prem)

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7
Q

What can cause neonatal jaundice before 24 hours?

A

Sepsis
ABO incompatibility
Rhesus haemolytic disease
Red cell anomalies

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8
Q

What can cause prolonged jaundice?

A
Breastfeeding
Sepsis
Hypothroidism
Cystic fibrosis
Biliary atresia
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9
Q

What are the features of kernicterus?

A
Lethargy
Poor feeding
Hypertonicity
Opisthotonus
Shrill cry
Yellow staining in brain
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10
Q

What are the long term sequellae of kernicterus?

A

Athetoid movements
Deafness
Reduced IQ

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