Neonatal Jaundice Flashcards
How common is neonatal jaundice?
60% of neonates
What is a complication of neonatal jaundice if not managed properly?
Kernicterus = permanent brain damage
What is the management of neonatal jaundice?
Phototherapy
If v. severe: exchange transfusion
What is physiological jaundice?
Hyperbilirubinaemia after 24 hrs
What are the causes of physiological jaundice? (4)
- Shorter RBC lifespan (increase bilirubin production)
- hepatic immaturity (decreased bilirubin conjugation)
- Absence of gut flora impedes elimination of gut flora
- Exclusive breastfeeding
When should you worry about neonatal jaundice?
Before 24 hours
Doesn’t fade by 14 days (term) or 21 days (prem)
What can cause neonatal jaundice before 24 hours?
Sepsis
ABO incompatibility
Rhesus haemolytic disease
Red cell anomalies
What can cause prolonged jaundice?
Breastfeeding Sepsis Hypothroidism Cystic fibrosis Biliary atresia
What are the features of kernicterus?
Lethargy Poor feeding Hypertonicity Opisthotonus Shrill cry Yellow staining in brain
What are the long term sequellae of kernicterus?
Athetoid movements
Deafness
Reduced IQ