Neonatal Infections Flashcards
What is sepsis?
designate a systemic condition of bacterial, viral, or fungal (yeast) origin that is associated with haemodynamic changes and other clinical manifestations and results in substantial morbidity and mortality
What is Early Onset of Sepsis?
<72hrs of life
What is Late Onset of Sepsis?
> 72hrs to 3 months
What causes EOS?
bacteraemia
pneumonia
What is common in LOS?
meningitis
What are the risk factors for neonatal infection?
maternal
neonatal
environmental
Why are neonates vulnerable to infection?
immature immune system
skin breaks
antibiotic treatment
mode of delivery
What are the 2 types of passive immunity?
Short Lived
maternal (innate)
Antibody Transfer (artificial)
What are the 2 types of active immunity?
Long Lived
infection (innate)
immunisation (artificial)
What are the modes of transmission of sepsis?
vertical transmission
horizontal transmission
What are the recommended vaccines before and during pregnancy?
MMR
Flu
Varicella (2 doses)
Covid
Pertussis (Tdap)
What are In-Utero Infections?
Congenital Infection
Viral
Bacterial
Protozoan
What are congenital Infection?
T-pallidum
Group B strep
Listeria monocytogenes
Haemophilus Influenza
Malaria (protozoa)
What does TORCH stand for?
Toxoplasmosis
Other (hep)
Rubella
Cytomegalovirus - CMV
Herpes Simplex Virus - type 2
What is Parvovirus B19?
Slapped cheek syndrome
