neonatal infection

Question 1

when is neonate

Answer 1

first 28 days but adjust if PTD

Question 2

Define early onset neonatal infection

Answer 2

3-5 days or less than 48 hours

Question 3

Most common infections

Answer 3

Group B strep, 1/3 of all women colonised
Ecoli
Listeria is very rare

Question 4

What is group B strep

Answer 4

gram postive coccus catalase negative

B haemolytic

Question 5

How does Group B strep present in child

Answer 5

Disseminated infection
Sepsis
Meningitis

Question 6

How long is treatment for meningitis from strep

Answer 6

Treatment for meningitis is 6 weeks of ABx esp if abscess in brain

Question 7

How long is treatment for sepsis from strep

Answer 7

Treatment for sepsis is 7-14 days

Question 8

E coli is what

Answer 8

gram negative rod

Question 9

Which antigen E coli is pathogenic

Answer 9

K1 antigen

Question 10

Symptoms of Ecoli infection

Answer 10

Sepisis from urinary tract
Bacteraemia
Meningitis so needs LP

Question 11

Symptoms of Listeria

Answer 11

sepsis in mother and baby can be very fatal and fast

Question 12

what kind of bacteria is Listeria

Answer 12

gram positive rod

Question 13

Which culture is Listeria grown on

Answer 13

Blood agar

Question 14

Early onset maternal sepsis risk factors

Answer 14

PROM/PTD
Fever
Foetal distress
Meconium staining

Question 15

Early onset sepsis baby risk factors

Answer 15

Birth asphyxia
RDS
low BP
Acidosis 
Neutropenia
Jaundice

Question 16

Routine Investigations for Early onset sepsis

Answer 16

FBC
CRP
BC
Deep ear swab routine for maternal fluids
LP
CXR

Question 17

Treament for early onset neonatal sepsis

Answer 17

ABC, nutrition

Benzylpenicillin and Gentamicin

Question 18

Late onset sepsis definition

Answer 18

48-72 hours

Question 19

Late onset sepsis most common organism

Answer 19

Mainly Coagulase negative Staph - CoNS which is on skin of babies

Question 20

Other late onset sepsis common organisms

Answer 20

GBS

EColi, S Aureus and resistant gram negative bacteria

Question 21

Clinical features of late onset sepsis

Answer 21

non specific like bradycardia, poor feeding

Question 22

Treatment of late onset sepsis

Answer 22

Start broad spec Abx
Receive negative cultures, stop Abx after 36 hrs
If some suspicion of sepsis, 5 days Abx