Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Bacteriology > Neisseria Gonorrhoea > Flashcards

Neisseria Gonorrhoea Flashcards

1
Q

Which is the second commonest bacteria in the UK?

A

Neisseria Gonorrhoea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What makes neisseria Gonorrhoea a major public health concern?

A

It’s antimicrobial resistance.
Its persistence and
Its association with poor reproductive health outcomes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the factors that divide gonococci into 4 kellog types?

A

Colonial appearance.
Ability to auto aggultinate
Virulence.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Name the four kellog types of gonorrhoea.

A

Type 1-4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Name the two kellog types that are more virulent and posses many fimbrae

A

Type 1 and 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which kellog is avirulent and non- fimbrate

A

Type 3-4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What’s the fxn of fimbrae on the gonococci

A

It’s aids in attachment in mucosa surfaces.

And confers resistance from phagocytosis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

List the two epidemiological typing used by gonococci:

A

Auxotyping (using nutritional requirements of arginine, proline, hypoxanthine and uracil.et.c) HAPU

Monoclonal antibodies.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

List the clinical manifestation of gonococci in males:

A

Acute urethritis accompanied with purulent urethral discharge.

Water can perineum as a secondary complication

Epididymitis

Epididorchitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What’s the incubation period of gonococcal in males

A

2-7 days.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is water can perineum?

A

This is abscess and sinus formation in the perineum as a result of gonococcal spread to peri urethral areas.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Is gonococcal more severe in females? +

A

No,
Its asymptomatic in females

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

List the clinical manifestation of gonococci in females.

A

Mucopurulent cervicitis(most common presentation)

Vulvovaginitis.

Salpingitis

Pelvic inflammatory disease

Fitz Hugh Curtis syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

In what age grade is Vulvovaginitis seen in and why?

A

Prepubertal girls.
Post menopausal women.

Reason : due to low oestrogen level.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Why doesn’t Vulvovaginitis affect adult females

A

Because of low vagina pH and
Thick stratified squamous epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Does this clinical manifestation affect the female sterility?

A

Yes.
It leads to sterility.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is Fitz Hugh Curtis syndrome

A

Perihepatic inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What’s the clinical manifestation of gonococci in neonates?

A

Ophthalmia Neonatorum.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

When does purulent eye discharge occur in neonates

A

2-5 days after birth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

How does a neonates contact Ophthalmia neonatorum?

A

Through birth via a gonococcal colonised maternal genital flora

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Treatment of ophthalmia neonatorum

A

Silver nitrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

List secondary local complications of gonococcal

A

Epididymitis
.
Salpingitis

Metastatic complications like arthritis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are the other(tertiary ) manifestations of gonococcal infection.

A

Disseminated gonococcal infection :

skin lesion, painful joints and fever.

Ophthalmia neonatorum.

Perihepatic inflammation.

And rarely endocarditis and meningitis.

24
Q

How are asymptomatic rectal and pharyngeal infection often identified.

A

Through contact tracing

25
Q

Does gonococcal enhance HIV transmission?

A

Yes

26
Q

List the microscopic features :

A

Gram negative,
Intracellular,
Aerobic,
Diplcocci,

27
Q

Mentioned the culture steps of gonococcal investigation.

A
  1. Collect urethral swabs from males and endocervical swabs from females.

2) Innoculate into a selective media and place in a rich CO2 culture.

28
Q

Which is the most sensitive laboratory investigation regimen and why?

A

NAAT: Nucliec acid amplification test.

Detects both symptomatic and asymptomatic infections.

96% more sensitive than culture

29
Q

Which bacteria infxn accompanies gonorrhea infection.

A

Chlamydia trachomatis

30
Q

Which sample is taken for disseminated gonococcal infection.

A

Synovial,
Blood culture.

31
Q

What’s the transport media for gonococcal

A

Charcoal impregnated swap

32
Q

List the culture media for gonococcal

A

Chocolate media,
Mueller Hinton agar

33
Q

List the selective agar

A

Thayer- Martins,
Modified new York City media.
Martin-Lewis media

34
Q

What’s the treatment for gonorrhea meningitidis

A

Ceftriaxone and azithromycin

35
Q

What are the agents for bacteria of non gonococcal urethritis

A

Chlamydia trachomatis.
Ureaplasma urealyticum.
Mycoplasma hominis

36
Q

What are the agents for virus of non gonococcal urethritis

A

Herpesvirus.
Cytomegalovirus

37
Q

What is the agent for parasite cause of non gonococcal urethritis

A

Trichomonas vaginalis

38
Q

What is the fungal cause of non gonococcal urethritis

A

Candida albicans

39
Q

What’s the onset for gonococcal urethritis

A

48hrs(2days)

40
Q

When is the onset for non gonococcal urethritis

A

Longer than 1 week

41
Q

What is the features of the discharge in gonococcal urethritis

A

Purulent(flows like seed)

42
Q

What is the features of the discharge in non gonococcal urethritis?

A

Mucous to mucopurulent

43
Q

What is the complication of non gonococcal urethritis?

A

Reiters syndrome :
Xterised by Conjunctivitis, urethritis, arthritis and mucosa lesions.

44
Q

What are the common complications in gonococcal and non gonococcal urethritis in MALES:

A

Epididymitis.
Prostatitis..
Seminal vasculitis.
Balanitis

45
Q

What are the common complications in gonococcal and non gonococcal urethritis in FEMALES:

A

Salpingitis,
Fitz Hugh Curtis syndrome.
Pelvic inflammatory disease.

46
Q

Which culture is used for chlamydia diagnosis :

A

McCoy and Hela cell lines

47
Q

Which culture is used for trichomonas diagnosis :

A

Trophozoites

48
Q

Which culture is used for candida diagnosis :

A

Detection of budding yeast cells in discharge.

49
Q

What is used to diagnose HSV and chlamydia infxn? n

A

PCR

49
Q

What is used to diagnose HSV and chlamydia infxn? n

A

PCR

50
Q

Treatment for chlamydia

A

Doxycycline

51
Q

Treatment for trichomonas

A

Metronidazole

52
Q

Treatment for candida

A

Clotrimazole (vagina cream)

53
Q

Where is the habitat of non pathogenic neisseria in the body

A

Upper respiratory tract(they’re commensals there)

54
Q

List the examples of Non pathogenic neisseria.

A

N. Lactamica
N. Mucosa.
N. Subflava.
N. Flavescens.
N. Elongata.
N. Sica.
N. Cinera.
N. Weaveri.
N. Polysaccharea

55
Q

Name the occasionally invasive disease of non pathogenic neisseria.

A

Meningitis,
Endocarditis,
Bacteriemia
Pericarditis,
Osteomyelitis.
Ocular infections.
Empyema.

Bacteriology (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions