Neisseria

Question 0

Two important Neisseria?

Answer 0

Neisseria gonorrhoeae
&
Neisseria meningitidis

Question 1

Neisseria:

Answer 1

• gram negative intracellular diplococcus
• many are normal flora on mucous membranes of the upper respiratory tract & urogenital tract.
• sensitive to the environmental conditions outside of the body.
• 2 important pathogens

Question 2

Neisseria gonorrhoeae:

Answer 2

• causative agent of gonorrhea since 1965. Most common reported STD.
• can affect urethra, endocervix, anal canal, pharynx, conjunctiva.
• bacteria collect and thrive In the neutrophils.
• 2-7day incubation period.
• males:95% will have a yellow outlet discharge from urethra & painful urination, can lead to sterility.
• females:may be asymptomatic. Urethral/ vaginal discharge painful urination. Lower abdominal pain. About 50% will have symptoms may progress to PID, sterility, ectopic pregnancy.

Question 3

Neisseria Meningitidis:

Answer 3

• can be commensal inhabitant of upper respiratory tract.
• can be spread by oral secretion or respiratory droplet.
• a leading cause of bacterial meningitis.
• inflammation of the meninges, begins as sore throat, leads to bacteremia and then meningitis.
• most symptoms are caused by endotoxins: fever,headache,lesson appetite, stuff neck.
• bacteria founding CSF in blood.
• treated with penicillin, cephalosporins,rifamin, sulfonamide.
• forms a polysaccharide capsule used in vaccine for military and in managing epidemics.