Negative Feedback Loop Flashcards

1
Q

What occurs when blood pressure is low?

A

Kidneys determine blood pressure, a decrease will then cause renin to be released

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2
Q

Renin

A

An enzyme that causes angiotensin to be converted into angiotensin I, found in the kidneys

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3
Q

Angiotensin I

A

IThis is then converted to angiotensin 2 by ace found in the lungs

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4
Q

Angiotensin 2

A

Controls regulates aldosterone which then contributes to the retention of sodium and with water, hence creates an increased thirst, vasoconstrictions, and potassium excretion

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5
Q

Adh

A

Regulates fluid volume, antideuntic hormone that decreases urine output and hold onto water, stimulated when there is an increase in blood concentration,produced in the hypothalamus posterior pituitary

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6
Q

Hypovolemia

A

Dehydration
Deficit in fluid volume
from inadequate intake or excess excretion, decreased intro vascular and extracellular fluid volume which often triggers r-a-a-s to increase heartrate, constrict arteries and increase heart contractility

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7
Q

Hypervolemia

A

Excess increase of fluid in the extracellular compartment. Causing a retention in sodium and water, mean arterial blood pressure which inhibits antidieretic hormone and aldosterone, which should increase sodium ad water elimination.

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8
Q

Aldosterone

A

Produced in the rats negative feedback loop followed by angiotensin 2, it is meant to retain sodium and excrete potassium

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9
Q

Clinical manifestations of hypovolenia

A

Thirst, dry mucous membrane, weight loss, flattered neck veins, ‘ diminished skin turgor, long capillary refill >3 seconds, decreased urine output, increased heart rate, decreased blood pressure - a-l - C -

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10
Q

Water intoxication

A

Hypotonic hypovolemia, decreased sodium concentration, potential causes, diuretic therapy that inhibits antidiuretic hormone

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11
Q

Diuretic

A

Opposite of an antidiuretic hormone, instead makes you use the restroom, excretes sodium and water

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12
Q

Dehydration: treatments

A

Lactated ringers_intraveneous with isotonic solutions of normal saline

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13
Q

Treatments for water intoxication

A

Hypertonic saline solutions and loop diuretic to increase water elimination

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14
Q

RAAS system purpose

A

Meant to decrease urine output, increase sodium retention and via ADH hormone and Angiotensin 2

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15
Q

Complications of hypovolemia

A

Hypotension
Shock
Kidney injury
Tissue hypoxia

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