NCDs, maternal health, mental health, child health Flashcards
What proportion of maternal and neonatal deaths are associated with anaemia
40%
Anaemia diagnostics in low resource areas
skin prick
colour chart - conjunctival pallor
common causes of anaemia in sub saharan Africa
Bacteremia (non-typhi salmonella - asymptomatic)
Malaria
Hookworm
HIV
G6PD
Vit A or B12 deficiency
What feature of sickle cell anaemia improves prognosis
High HbF = better prognosis
Clinical features of sickle cell
Bony deformities
Haemolysis
Organ damage from sickle cells
Pain crisis
Intercurrent infections → thrombi to spleen causing hyposplenism
Strokes/TIA
Acute splenic sequestration
Young children - dactylitis
Older children - pain in long bones
Adults - painful ulcers, non-healing
AVN
Sickle cell management
Do not transfuse unless Hb low
Folate
Pain Mx
Treat infection, fluids, O2.
Prophylactic penicillin
Immunisations
Hydroxyurea - increases proportion of HbF
What was the outcome of the FEAST trial?
increased mortality with bolus fluids in children with Sepsis in African setting
Outcome of sepsis protocol in Africa
‘usual care’ had a better mortality outcome than the sepsis protocol
Long term outcomes of sepsis
Increased mortality over the next 5 years even when compared to age and disease matched controls.
What are neutralizing antibodies
Antibodies which are effective in preventing infection - ie. active early when virus enters the body. Stops initial infection from taking hold. Patient never becomes unwell or infective.
What does ETAT stand for?
Emergency triage, assessment and treatment
What are the ETAT priority signs?
Trauma, Tiny, Temp
Pallor, pain, poisoning
Restless, respiratory distress, urgent referral
Malnutrition, oedema, burns
What are the ETAT emergency signs?
A- airway obstruction, central cyanosis
B - not breathing, severe resp distress
C - cold skin + cap refill >3 secs + weak and fast pulse
C - convulsing, coma
D - diarrhoea + lethargy/sunken eyes/ slow skin pinch/ not drinking
Management of child airway as per ETAT
Open the airway
<1year - neural position
>1 year - sniffing position
Management of child breathing as per ETAT
Respiratory distress:
- sit patient up
- give O2 if severe
- give ABx to all - Amoxil - add gent if severe
- maintenance fluids if severe (NO BOLUS)
- if wheeze present give salbutamol spacer
- CPAP if severe
Management of child circulation as per ETAT
Management of Shock
Give blood if Hb <6
Give Hartmans/saline over 30mins - slow to 1 hour and add glucose if malnourished.
If resolved - give maintainence fluids- add ReSoMal if malnourished
If not resolved - give blood - add ReSoMal if malnourished