NBRC Test Questions Flashcards

1
Q

Animal studies are designed to accomplish which of the following?

a. General effect on the organism
b. Effects on specific organs
c. Toxicology studies
d. All the above

A

d. All the above

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2
Q

Studies involving human subjects occur during which stage of the drug approval process?

a. Chemical identification
b. IND approval
c. NDA
d. Internal review

A

b. IND approval

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3
Q

Which of the following is the generic name for the antiasthmatic drug Accolate?

a. Proventil
b. Zafirlukast
c. ICI 204,219
d. ED-AA

A

b. Zafirlukast

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4
Q

If you are looking up a drug in a reference source that has color charts that identify drugs, lists manufacturers, and tells how the drugs work, you are looking in the

a. Hospital Formulary
b. Hospital Reference Source
c. Physicians’ Desk Reference
d. Drug Handbook

A

c. Physicians’ Desk Reference

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5
Q

Which of the following is an advantage of aerosolized agents by inhalation?

a. Aerosol doses are larger than those used for the same purpose and given systemically.
b. Aerosolized agents have more side effects than those given systemically.
c. Aerosolized agents have a slower onset of action.
d. Drug delivery is targeted to the respiratory system and is painless.

A

d. Drug delivery is targeted to the respiratory system and is painless.

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6
Q

An order has been written for a patient to receive an aerosolized bronchodilator tid. This would indicate the patient should receive the treatment

a. Four times a day
b. Three times a day
c. Once a day
d. Every 3 hours

A

b. Three times a day

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7
Q

An agent that will relax bronchial smooth muscle and reduce airway resistance to improve ventilatory flow rate in chronic obstructive pulmonary disease (COPD) and asthma is

a. Adrenergic
b. Corticosteroid
c. Antiinfective
d. Mucoactive

A

a. Adrenergic

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8
Q

A patient has been ordered to receive a corticosteroid. This could indicate the patient has a need for

a. Bronchial smooth muscle relaxation
b. Thinning of mucus
c. Increase in lung compliance
d. Reduction and control of inflammatory response in the airway

A

d. Reduction and control of inflammatory response in the airway

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9
Q

This is an agent that is used to rid the body of excess fluid that may accumulate in the lungs.

a. Antiinfective
b. Antithrombolytic
c. Diuretic
d. Anticoagulant

A

c. Diuretic

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10
Q

As you enter a patient’s room, you notice a sign above the bed that reads “NPO.” This would indicate

a. Administer medications by mouth only
b. Administer drugs by IV only
c. Nothing by mouth
d. No needlesticks

A

c. Nothing by mouth (nothing per os)

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11
Q

This legislation put more controls on biologic agents and toxins and was passed in 2002.

a. Prescription Drug User Act
b. Supplemental Drug and Enforcement Act
c. Bioterrorism Act
d. Amendment Act

A

c. Bioterrorism Act

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12
Q

A class of drugs including montelukast and zileuton is used to

a. Reduce infection
b. Prevent the onset of asthmatic response
c. Help increase surface tension in the alveoli
d. Reduce pulmonary hypertension

.

A

b. Prevent the onset of asthmatic response

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13
Q

A specific aerosolized agent used to inhibit or eradicate specific infective agents in patients with CF is:

a. Pentamidine
b. Tobramycin
c. Ribavirin
d. Zanamivir

A

b. Tobramycin

  • Pentamdine is also an antiinfective agent, but typically is used to treat Pneumocystis jirovecci
  • Ribavirin is also antiinfective, but treat RSV
  • Zanamivir is also an antiinfective, but not a specific aerosolized agent.
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14
Q

A prostacyclin analog used to treat pulmonary hypertension would include

a. Iloprost
b. Zileuton
c. Lucinactant
d. Beractant

A

a. Iloprost: prostacyclin analog

b. Zileuton: antiasthmatic
c. Lucinactant: exogenous surfactant
d. Beractant: exogenous surfactant

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15
Q

On reading a patient’s medical history, it is learned the patient has a diagnosis of HIV infection. This would indicate the causative organism of the patient’s pneumonia is likely

a. Pseudomonas aeruginosa
b. Streptococcus aureus
c. Haemophilus influenzae
d. Pneumocystis carinii (jiroveci)

A

d. Pneumocystis carinii (jiroveci)

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