Nature & Sources of Drugs Flashcards

1
Q

study of biological effects of drugs

A

Pharmacology

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2
Q

study of drugs and their origin, nature properties and effects on living organisms

A

Pharmacology

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3
Q

Branch of pharmacology that uses drugs to treat, prevent, and diagnose disease

A

Clinical Pharmacology

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4
Q

a chemical substance of known structure, other than a nutrient of an essential dietary ingredient which when administered to a living organism produces a biological effect.

A

Drug

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5
Q

True or false.
Tablets are 100% drug.

A

False

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6
Q

Fillers and inert substances, generally called ____ are used in drug preparation to allow the drug to take on a particular size and shape to enhance drug dissolution.

A

Excipients

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7
Q

True or False.
Pharmacological Drug is also called Medicine.

A

True

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8
Q

Division of Drugs

A

Medicinal and Non-medicinal

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9
Q

Six Major Sources of Drugs

A

Plant
Animal
Mineral/Earth
Microbiological
Semi synthetic/Synthetic
Recombinant DNA Technology

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10
Q

Oldest source of drugs

A

Plant sources

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11
Q

Leaves of this are the source of Digitoxin and Digoxin which are cardiac glycosides

A

Digitalis Purpurea

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12
Q

Leaves of this give oil to ___ which is important for couch syrup

A

Eucalyptus

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13
Q

___ leaves gives nicotine.

A

Tobacco

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14
Q

___ leaves gives atropine

A

Atropa Belladonna

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15
Q

___ root gives ____, used to induce vomiting as in accidental poisoning. It has amoebicidal properties.

A

Ipecacuanha, Emetine

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16
Q

Roots of ___ gives ___, a hypotensive agent.

A

Rauwolfia serpentina, reserpine

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17
Q

___ was used for hypertension treatment

A

Reserpine

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18
Q

____ gives quinine and quinidine, which are antimalarial drugs. ___ also has anti-arrhythmic properties.

A

Cinchona bark, quinidine

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19
Q

___ gives atropine, which is anticholinergic
___ gives hyosine, which is also anticholinergic

A

Atropa belladonna, Hyoscyamis Niger

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20
Q

___ gives tuboqurarine, skeletal muscle relaxant used in general anesthesia.

A

Chondrodendron tomentosum

21
Q

Source of insulin in animals, used in treatment of Diabetes

A

Pancreas

22
Q

Urine of pregnant woman

A

gives human chorionic gonadotropin (hCG) used for the treatment of infertility

23
Q

A source of thyroxin, used in hypertension.

A

Sheep thyroid

24
Q

Is used as source of vitamin A and D

A

Cod liver

25
Q

source of pituitary gonadotropins, used in treatment of infertility.

A

Anterior Pituitary

26
Q

Used in preparation of vaccines

A

Blood of animals

27
Q

contains pepsin and trypsin, digestive juices used in treatment of peptic diseases in the past. Nowadays better drugs have replaced them.

A

Stomach tissue

28
Q

Used in treatment of iron deficiency anemia

A

Iron

29
Q

Used in syphilis

A

Mercurial salts

30
Q

Used in wounds and in eczema

A

Zinc oxide paste

31
Q

3 sources with antiseptic properties

A

Iodine, Fluorine, Borax

32
Q

Used in anti dandruff shampoo

A

Selenium as selenium sulphide

33
Q

used in preparation of liquid paraffin

A

Petroleum

34
Q

Type of drug source where nucleus and chemical structure is altered

A

Synthetic

35
Q

Example of synthetic source

A

Emetine Bismuth Iodide

36
Q

Type of drug source when nucleus of drug obtained from natural source is retained but chemical structure is altered.

A

Semi-synthetic

37
Q

Examples of Semi-synthetic

A

Apomorphine, Diacetyl morphine, Ethinyl Estradiol, Homatropine, Ampicillin and Methyl testosterone

38
Q

Most of the drugs used nowadays (such as anti anxiety drugs, anti convulsants) are ___ forms.

A

Semisynthetic

39
Q

Fungus which gives penicillin

A

Penicillium notatum

40
Q

___ give Streptomycin

A

Actinobacteria

41
Q

___ such as gentamicin and tobramycin are obtained from streptomycis and micromonosporas.

A

Aminoglycosides

42
Q

Involves cleavage of DNA by enzyme restriction endonucleases

A

Recombinant DNA Technology

43
Q

More than thirty vaccines are being distributed, though highly effective ___ vaccines have become the most sought after worldwide.

A

mRNA vaccines

44
Q

3 types of vaccines

A

mRNA
Viral vector
Protein subunit

45
Q

Medicinal drugs are used for

A

Prevention, treatment, and diagnosis

46
Q

Non-medicinal drugs are used for

A

Recreational purposes

47
Q

Used in treatment of rheumatoid arthritis

A

Gold salts

48
Q

True or false. Drug can be obtained in pure form is an advantage of Recombinant DNA technology.

A

True

49
Q

True or false. In using Recombinant DNA technology, drug is less antigenic which is an advantage.

A

False. It is a disadvantage.