natural selection and genetic modification Flashcards

topic 4

1
Q

explain Charles Darwin’s theory of evolution by natural selection

A
  1. individuals in a population show genetic variation due to differences in their alleles
  2. predation and competition for resources and disease act as selection pressures
  3. better adapted characteristic to the selection pressures in their environment give the individuals a better chance of survival
  4. breed successfully and alleles (+genes) are passed on
  5. organisms evolve
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2
Q

Explain how the emergence of resistant organisms supports
Charles Darwin’s theory of evolution including antibiotic
resistance in bacteria

A
  • makes the bacteria better adapted to an environment
  • where antibiotics (selection pressure) are present
  • so antibiotic resistance becomes more common in the population over time
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3
Q

another example of a resistant organism

A

rats resistant to poison

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4
Q

what is a selection pressure

A
  • something that affects an organisms chance of surviving and reproducing
  • ex predation, competition, disease
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5
Q
A
  1. some bacteria in population are more resistant to antibiotics
  2. antibiotic is added to the population of bacteria (selection pressure)
  3. some survive
  4. survivors reproduce and pass on resistant alleles/genes
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6
Q

describe the evidence for human evolution based on fossils
a) Ardi from 4.4 million years ago

A
  • big toe to climb trees
  • long arms and short legs
  • brain size like a chimpanzees
  • structure of legs = walked upright
  • structure of hand bones = didn’t use hands to walk
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7
Q

describe the evidence for human evolution based on fossils-
b) Lucy from 3.2 million years ago

A
  • arched feet for walking not climbing
  • no ape like big toe
  • size of arms and legs between an apes and a humans
  • brain slightly larger than Ardi’s - still similar to a chimps brain
  • structure of leg bones and feet = walked upright and more efficiently to Ardi
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8
Q

describe the evidence for human evolution based on fossils
c) Richard Leakey’s discovery of fossils from 1.6 million years ago

A

found fossils of homo erectus
- short arms and long legs = more human
- larger brain size and more similar to humans that Lucy’s
- structure of legs and feet = better at walking upright than lucy

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9
Q

who came first Ardi or Lucy or Homo erectus

A

oldest = Ardi
middles = Lucy
youngest = homo erectus

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10
Q

describe the evidence for human evolution based on stone tools
a) the development of stone tools over time => HOMO HABILIS (1)

A
  • simple stone tools by hitting rocks together
  • could scrape meat from bones or crack bones open
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11
Q

describe the evidence for human evolution based on stone tools
a) the development of stone tools over time =>
HOMO ERECTUS (2)

A
  • sculpted rock s into shapes
  • more complex
  • hunt dig chop scrape meat
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11
Q

describe the evidence for human evolution based on stone tools
a) the development of stone tools over time =>
HOMO NEANDERTHALENSIS (3)

A
  • more complex
  • flint tools, pointed tools and wooden spears
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12
Q

describe the evidence for human evolution based on stone tools
a) the development of stone tools over time =>
HOMO SAPIENS

A
  • flint tools
  • pointed tools including arrow heads, fish hooks and needles
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13
Q

describe the evidence for human evolution based on stone tools
b) how these can be dated from their environment

A
  1. looking at structural features - simpler likely to be older
  2. stratigraphy - study of rock layers - older rock layers found below younger layers (tools or fossils found in deeper layers = older)
  3. carbon-containing material - Carbon-14 dating used to date the material
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14
Q

Describe how genetic analysis has led to the suggestion of the three domains rather than the five kingdoms classification method

A
  • technology developed
  • Woese found that some members of Prokaryote Kingdom were not as closest related using genetic analysis
  • he suggested all organisms divided into 3 groups “domains” = archaea, bacteria, eukarya
  • then the 3 domains are split into smaller groups used in the five kingdom system
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15
Q

what are the 5 kingdom domains

A
  • animals
  • plants
  • fungi
  • prokaryotes
  • protists
    and then split into smaller groups
  • phylum, class, order , family, genus, SPECIES
16
Q

what are the 3 domains

A
  • archaea
  • bacteria
  • eukarya
17
Q

explain selective breeding

A
  1. select characteristics you want from existing stock
  2. breed them with each other
  3. select best offspring and breed them together
  4. continue over several generations - eventually all offspring will have the characteristic
18
Q

explain selective breeding’s impact on food, plants and domesticated animals (disadvantages of selected breeding)

A
  • reduces the gene pool of alleles ( number of different alleles
  • inbreeding can cause health problems
  • little variation is bad for if a new disease appears
19
Q

explain how selective breeding reduces the gene pool

A
  • reduces number of different alleles
  • as the “best” animals or plants are used for breeding - and are closely related
  • = inbreeding
20
Q

how does inbreeding cause health problems

A
  • there’s more chance of organisms inheriting harmful genetic defects when the gene pool is limited
21
Q

how does selective breeding cause serious health problems if a new disease appears

A
  • not much variation so less chance of resistance alleles being present
  • all stock are closely related to each other
    • so if one dies to disease they likely will all die
22
Q

advantages of selective breeding in agriculture

A
  • genetic variation means some cattl ehave better characteristics for proudcing meat
  • to improve meat the farmer may breed best cows together
  • to get the best offspring
23
Q

advantages of selective breeding in medical research

A
  • investigating reasons behind alcoholism
  • rats bred with strong or weak preference to alcohol
  • researchers compare differences in the rats like behaviour and way their brains work
24
2 advantages of selective breeding
- agriculture - medical research
25
what is genetic engineering (definition)
a process which involves modifying the genome of an organism to introduce desirable characteristics
26
the main stages of genetic engineering
1. restriction enzymes 2. ligase 3. sticky ends 4. vectors
27
describe main stages of genetic engineering a) restriction enzymes
- restriction enzymes recognise specific sequences of DNA and cut the DNA at these points - the pieces of DNA are left with sticky ends where they've been cut
28
describe main stages of genetic engineering b) ligase
- ligase enzymes are used to join 2 pieces of DNA together at their sticky ends - recombinant DNA
29
what is recombinant DNA
2 different bits of DNA stuck together
30
describe the main stages of genetic engineering d) vectors
- a vector is something used to transfer DNA into a cell - 2 types plasmids viruses
31
what are plasmid vectors
small, circular molecules of DNA that can be transferred between bacteria
32
what are viruses vectors
viruses insert DNA into the organisms they infect
33
describe all the stages of genetic engineering
1. DNA you want to insert is cut out with a restriction enzyme, the vector DNA is cut open using same restriction enzyme 2. vector DNA and DNA inserting are left with sticky ends 3. ligases join pieces of DNA together to make recombinant DNA 4. recombinant DNA is inserted into other cells 5. these cells use gene you inserted to make the protein you want
34
benefits of genetic engineering in modern agriculture
- resistant to herbicides => increases crop yield
35
risks of genetic engineering in modern agriculture
- transplanted genes may get out into the environment - adversely affect food chains or human health
36
benefit of genetic engineering in medicine
- genetically engineering bacteria can produce human insulin - researches have transferred human genes that produce useful proteins into sheep and cows - proteins can be extracted from the animal s - animals with organs suitable for organ transplantation into humans may be produced
37
risks of genetic engineering in medicine
- hard to predict what effect modifying its genome will have on the organism - lots of genetically modified embryos don't survive or suffer from health problems later on