Natural Killer Cells Flashcards

1
Q

General Features of NK cells

A
  • originate from bone marrow
  • live for about a week
  • are found in the blood, spleen, and liver
  • migrate to tissues during inflammation
  • do not possess receptors (TCR, BCR)
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2
Q

What are the cell trafficking receptors on the NK cells?

What are their functions?

A
  • chemotactic: direct cells to site of infection
  • cytokine: activate the NK cells
  • adhesion: help ensure survival of NK cells at the site of infection
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3
Q

Describe the morphology of NK cells

A
  • called large granular lymphocytes

- contain lyric granules

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