Major Histocompatibility Complex

Question 1

On what cells are MHC Class 1 molecules expressed?

Answer 1

all nucleated cells

Question 2

On what cells are MHC Class 2 molecules expressed?

Answer 2

only on antigen presenting cells

Question 3

What cells does MHC Class 1 present to?

Answer 3

CD8+ T lymphocytes

Question 4

What cells does MHC Class 2 present to?

Answer 4

CD4+ T lymphocytes

Question 5

What is the function of MHC Class 3 molecules?

Answer 5

function in the innate immunity

Question 6

What is the structure of MHC Class 1 molecules?

Answer 6

an alpha chain (1-3)
a beta-microglobin chain
a bound peptide

Question 7

What is the binding groove made up of on the MHC class 1 molecule?

Answer 7

alpha 1 and alpha 2

Question 8

What is the structure of MHC Class 2 molecules?

Answer 8

an alpha chain (1-2)
a beta chain (1-2)
a bound peptide

Question 9

What is the binding groove made up of on the MHC class 2 molecule?

Answer 9

alpha 1 and beta 1

Question 10

What type of antigen does MHC Class 1 present?

Answer 10

endogenous

Question 11

What type of antigen does MHC Class 2 present?

Answer 11

exogenous