Nasal Polypi Flashcards
Nasal polypi are
non-neoplastic masses of oedematous nasal or sinus mucosa
two main varieties:
Bilateral ethmoidal polypi.
Antrochoanal polyp.
AETIOLOGY of BILATERAL ETHMOIDAL POLYPI
- Chronic rhinosinusitis➡️ allergic and nonallergic origin (Nonal- lergic rhinitis with eosinophilia syndrome (NARES))
- Asthma
- Aspirin intolerance
- Cystic fibrosis due to abnormal mucus
- Allergic fungal sinusitis
- Kartagener syndrome
- Young syndrome
- Churg–Strauss syndrome
- Nasal mastocytosis.
Samter’s triad
nasal polypi, asthma and aspirin intolerance.
Kartagener syndrome
This consists of bronchiectasis sinusitis, situs inversus and ciliary dyskinesis
Young syndrome
consists of sinopulmonary disease and azoospermia.
Churg–Strauss syndrome
Consists of asthma, fever, eosinophilia, vasculitis and granuloma.
Nasal mastocytosis
It is a form of chronic rhinitis in which nasal mucosa is infiltrated with mast cells but few eosinophils. Skin tests for allergy and IgE levels are normal.
PATHOGENESIS of BILATERAL ETHMOIDAL POLYPI
Nasal mucosa, particularly in the region of middle meatus and turbinate, becomes oedematous due to collection of extracellular fluid causing polypoidal change. Polypi which are sessile in the beginning become pedunculated due to gravity and excessive sneezing.
PATHOLOGY BILATERAL ETHMOIDAL POLYPI
In early stages, surface of nasal polypi is covered by ciliated columnar epithelium like that of normal nasal mucosa but later it undergoes a metaplastic change to transitional and squamous type on exposure to atmospheric irritation. Submu- cosa shows large intercellular spaces filled with serous fluid. There is also infiltration with eosinophils and round cells.
SITE OF ORIGIN of BILATERAL ETHMOIDAL POLYPI
lateral wall of nose, usually from the middle meatus
Common sites for BILATERAL ETHMOIDAL POLYPI
uncinate process, bulla ethmoidalis, ostia of sinuses, medial surface and edge of middle turbinate
Allergic nasal polypi almost never arise from
the septum or the floor of nose
SYMPTOMS of BILATERAL ETHMOIDAL POLYPI
- Nasal stuffiness ➡️ leading to total nasal obstruction
- Partial or total loss of sense of smell
- Headache
- Sneezing and watery nasal discharge
- Mass protruding from the nostril
Headache in BILATERAL ETHMOIDAL POLYPI is due to
associated sinusitis
BILATERAL ETHMOIDAL POLYPI is Mc in age group
Adults
In BILATERAL ETHMOIDAL POLYPI Sneezing and watery nasal discharge due to
allergy
SIGNS of BILATERAL ETHMOIDAL POLYPI On anterior rhinoscopy
polypi appear as smooth, glistening, grape-like masses often pale in colour. They may be sessile or pedunculated, insensitive to probing and do not bleed on touch. Often they are multiple and bilateral