NARCOTIC ANALGESICS

Question 1

1. A synthetic analgesic agent which increases contractile
   activity of myometrium and ^relaxes the neck (cervix) of uterus^ was prescribed to a woman in ^labour^. Indicate this agent.
   A.Promedolum (trimeperidine)
   B. Omnoponum
   C. Analginum (methamizole)
   D. Morphine
   E. Fentanylum

Answer 1

Promedolum

Question 2

2. A patient has signs of acute ^ poisoning by morphine^: sharp miosis, loss of consciousness, decrease of the arterial blood pressure and Cheyne-Stokes respiration. Choose the proper antagonist to be given.
A. Naloxonum
B. Camphor
C. Lobeline
D. Cytitonum
E. Cordiaminum (nikethamide)

Answer 2

Naloxonum

Question 3

4. A 30 years old man was admitted to a hospital due to fracture of the crus with dislocation and expressed pain syndrome.^ Promedolum (trimeperidine)^ was introduced to eliminate pain. Indicate the mechanism of action of this drug.
   A. Stimulation of the opioid receptors in the
   CNS.
   B. Blockade of the opioid receptors in the CNS.
   C. Stimulation of dopamine receptors in the CNS.
   D. Blocade of GABA receptors in the CNS.
   E. Blocade of dopamine receptors in the CNS.

Answer 3

Stimulation of the opioid receptors in the

CNS

Question 4

5. Naloxone was introduced to a 25 years old woman because of intoxication by morphine. After injection the state of the woman became better. Indicate the mechanism of action of this drug.
   A. Blockade of the opioid receptors of the CNS.
   B. Blockade of GABA receptors of the CNS.
   C. Blockade of the serotonin receptors of the CNS.
   D. Blockade of benzodiazepin receptors of the CNS

Answer 4

Blockade of the opioid receptors of the CNS

Question 5

6. A drug addict was admitted to the emergency
   department in coma with signs of poisoning by opioid
   analgesics. What side effect of morphine contributed to the poisoning?

A. Tolerance 
В Euphoria
C. Obstipation
D. Inhibition of breathing
E. Reduction of diuresis

Answer 5

Tolerance

Question 6

7. A 52-years-old patient who had been suffering from urolithiasis was delivered to the emergency department with ^renal colic^.
   A doctor administered atropine together with opioid analgesic with spasmolytic activity to prevent development of the pain shock. Choose this drug.

A. Promedolum (trimeperidine) 
B. Tramadol
C. Ibuprofen
D. Ketorolac 
E. Morphine

Answer 6

Promedolum

Question 7

15. Indicate the synthetic opioid analgasic which
    possesses analgesic activity 100-400 times more than morphine.

A.Phentanyl
B. Promedolum (trimeperidine)
C. Pentazocin
D. Omnoponom
E. Codein

Answer 7

Phentanyl

Question 8

16. A patient with hip fracture was prescribed a narcotic analgetic. Its anesthetic action is determined by interaction with the following receptors: 
A Opiate receptors 
B Adrenoreceptors 
C Cholinoreceptors 
D Benzodiazepine receptors 
E GABA-ergic receptors

Answer 8

Opiate receptors

Question 9

17. Patient in the unconscious state was admitted to the emergency room. Skin is cold, pupils are delayed, breathing is heavy, with cycles of theCheyne-Stokes type, blood pressure is decreased, urinary bladder is overloaded.
    Poisoning with what substance is the most likely?

A Narcotic analgesics
B Sedatives
C Non-narcotic analgesics
D М-cholinergic antagonists

Answer 9

Narcotic analgesics

Question 10

18. A 4 year old child was admitted to the orthopaedic department with shin fracture together with displacement. Bone fragments reposition requires preliminary ^analgesia^.
    What preparation should be chosen?

A Promedol
B Analgin
C Morphine hydrochloride
D Panadol

Answer 10

Promedol

Question 11

19. Examination of a patient revealed extremely myotic pupils, sleepiness, infrequent Chain-Stoke’s respiration, urinary retention, slowing-down of heart rate, enhancement of spinal reflexes. What substance caused the poisoning?

A Morphine 
B Atropine 
C Phosphacole 
D Caffeine 
E Barbital

Answer 11

Morphine

Question 12

20. A patient suffering from initial hypertension has been taking an antihypertensive preparation ^for a long time^. ^Suddenly he stopped taking^ this preparation. After this his condition grew worse, this led to development of hypertensive crisis. This by-effect can be classified as:

A Abstinence syndrome 
B Cumulation 
C Tolerance 
D Sensibilization 
E Dependence

Answer 12

Abstinence syndrome