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Pharmacology > HYPNOTIC, ANTIEPILEPTIC, ANTIPARKINSONIC AGENTS > Flashcards

HYPNOTIC, ANTIEPILEPTIC, ANTIPARKINSONIC AGENTS Flashcards

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1
Q

The patient of 70 years has appealed to the doctor with
complaints of superficial ^short-term sleep^ with ^often awakenings^ caused by sense of ^internal tension, anxiety, fear^. The diagnosis has been made as: ^senile sleeplessness^.
Make a rational choice of a hypnotic agent in the given
situation.
A.Nitrazepam
B. Aethaminalum-natrium (pentobarbital)
C. Phenobarbital
D. Bromisovalum
E. Chloral hydrate

A

Nitrazepaam

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2
Q

The patient suffering from ^parkinsonism^ has been
treating for a long time by the drug with central
cholinolytic mechanism of action which efficiency has
gradually decreased. Indicate drug which should be
administered instead of used one for improving of
antiparkinsonic action?
A. Levodopa
B. Cyclpdolum
C. Mydocalmum
D. Tropacinum
E. Bellataminalum

A

Levodopa

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3
Q
  1. A patient had been suffering from ^Parkinson’s disease^
    was admitted to the neurological department. Indicate the
    drug ^inhibitting cholinergic^ influences which is used for
    treatment of this disease.
    A.Cyclodolum (trihexyphenidyl)
    B. Levodopa
    C. Bromocriptin
    D. Midantanum (amantadine)
    E Selegilin
A

Cyclodolum

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4
Q 
A patient with convulsions was delivered by the 
ambulance to the hospital where the diagnosis of ^status epilepticus^ was given. Indicate the drug of the first choice 
in this situation.
A. Diazepam
B. Trimethinum (trimethadione)
C. Phenobarbital
D. Dipheninum (phenytoin) 
E.Carbamazepine
A

Diazepam

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5
Q

An attack of ^generalized tonoclonic^ convulsions
accompanied by ^loss of consciousness^ and general
suppression of the CNS developed in a patient after
trauma. What drug should be administered to this patient?
A. Phenobarbital
B. Cyclodolum (trihexyphenidyl)
C. Levodopa
D. Teturam (disulflram)
E. Midantanum (amantadine)

A

Phenobarbital

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6
Q

A 57-years-old woman was admitted to the hospital in
coma with inhibition of breathing, decreased BF’, signs of
cardiac insufficiency, decreased body temperature,
inhibition of reflexes. Due to anamnesis she had been
suffering from insomnia and a doctor administered to her
hypnotic agent. What drug can cause this poisoning?
A. Phenobarbital
В. Sodium bromide
C. Valeriana tincture
D. Scopolamine
E. Promedolum (trimeperidine)

A

Phenobarbital

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7
Q 
7. What agent should be administered to a patient in the 
case of
poisoning by barbiturates to normalize acid-base state?
A. NaHC03
B. Solution of arginine
C. Vitamins
D. Antibiotics 
E. Physiological solution of 
Natrium
A

NaHC03

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8
Q
  1. A 68-years-old patient was addressed to the doctor in the polyclinic with complaints of mental disorders after usage
    of Phenobarbital for a long period of time accompanied by
    ^insomnia^. What drug will the doctor administer to this
    patient as hypnotic
    A. Nitrazepam
    B. Cyclobarbital
    C. Chloral hydrate
    D. Natrii oxybutyras (oxybate sodium)
    E. Halopendol
A

Nitrazepam

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9
Q 
Determine the hypnotic drug which ^doesn't influence  the structure of sleep^.
A. Nitrazepam 
B. Phenobarbital
C. Barbital
D. Aethammalum-natrium (pentobarbital) 
E. Bromisoval
A

Nitrazepam

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10
Q
  1. The doctor administered a drug with a tranquilizing
    effect to the patient with ^insomnia after emotional disorders^. What drug was administered to the patient?
    A. Nitrazepam
    B. Phenobarbital
    C. Chloral hydrate
    D. Aethammalum-natrium (pentobarbital)
    E. Bromisova
A

Nitrazepam

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11
Q 
11. An 18-years-old patient complained of ^insomnia^ which manifested by not being able to sleep that led to fatigue, weakness, difficulty in learning the following day. The clinical examination revealed the following: the patient was easily irritated, emotionally unstable, heart rate and arterial pressure were altered during conversations. The doctor determined that insomnia was associated with a neurosis-like state and vegetovascular distonia. Make the most rational choice of hypnotic drug.
A. Nitrazepam
B. Phenobarbital
C. Chloral hydrate
D. Aethaminalum-natrium 
(pentobarbital)
E. Bromisoval
A

Nitrazepam

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12
Q
  1. A 65-years-old woman with Parkinson’s disease has been treated with ^cyclodolum^. Determine the mechanism of action of this drug.
    A Blockade of central cholinoreceptors
    B. Stimulation of dopamine receptors
    C. Stimulation of serotonine receptor
A

Blockade of central cholinoreceptors

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13
Q 
13. Determine the group of drug which can cause 
^medicinal Parkinsonism^.
A. Neuroleptics
B. Hypnotic drugs
C. Antidepressants
D. Tranquilizers
E. Nootropic agents
A

Neuroleptics

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14
Q
  1. A patient took reserpinum for the treatment of
    hypertonic disease for a long period of time. One day the patient felt muscles weakness, restriction of motion. Medicamentous parkinsonism was diagnosed. What drug should be administered to eliminate these side effects?
    A. Cyclodolum (trihexyphenidyl)
    B. Aminazinum (chlorpromazine)
    C. Haloperidolu
    P. Phenobarbital
    E. Tubocurarine
A

Cyclodolum

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15
Q 
15. A patient who suffers from  ^insomnia caused by emotional disorder^ was prescribed a hypnotic drug with tranquillizing effect. What hypnotic was prescribed? 
A Nitrazepam 
B Phenobarbital 
C Chloral hydrate 
D Sodium ethaminal 
E Bromisoval
A

Nitrazepam

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16
Q
  1. A 37 year old patient suffering from obliterating vascular endarteritis of lower limbs takes daily 60
    microgram/kilogram of phenylin. Because of presentations of convulsive disorder (craniocerebral trauma in
    anamnesis) he was prescribed phenobarbital. Withholding this drug caused nasal hemorhage. What is this
    complication connected with?

A Induction of enzymes of microsomal oxidation in liver caused by phenobarbital
B Aliphatic hydroxylation of phenobarbital
C Conjugation of phenylin with glucuronic acid
D Oxidative deamination of phenylin
E Inhibition of microsomal oxidation in liver caused by
phenobarbital

A

Induction of enzymes of microsomal oxidation in liver caused by phenobarbital

17
Q 
17. A patient consulted a physician about muscle rigidity, constrained movements, permanent arm tremor. The patient was diagnosed with Parkinson's disease. What preparation should be administered? 
A Levodopa 
B Phenytoin 
C Phenobarbital 
D Diazepam 
E Ethosuximide
A

Levodopa

Pharmacology (5 decks)

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