Narcolepsy Flashcards
1
Q
Cardinal features?
A
- Cataplexy
- Hypagognic Hallucinations
- Daytime sleepiness
- Sleep paralysis
2
Q
What is cataplexy?
A
Muscle weakness brought on by strong emotion.
-Laughing/ anger
3
Q
What is hypagognic hallucinations?
A
Vivid hallucinations on falling asleep.
4
Q
How common is it?
A
prevalence = 0.05%
Familial aspect
Linked to HLA DRB1 loci
5
Q
Treatment for Narcolepsy?
A
- Modafinil
- Clomipramide
- Sodium Oxybate
6
Q
Give examples of Neuromuscular Disorders
A
ALS Duchennes Muscular Dystrophy Cerebral Palsy Down's Syndrome Prader-Willi Syndrome
7
Q
What is Down’s Syndrome associated with?
A
OSAS
8
Q
Cerebral Palsy and sleep?
A
Delayed onset of sleep
Fragmented Sleep
9
Q
Duchenne’s Muscular Dystrophy?
A
- Possibility of death due to respiratory failure
- nocturnal desaturation
- improved quality of life with BiPAP
10
Q
Investigations for NMD
A
- Lung Function tests
- Early morning ABG
- Nocturnal Pulse Oximetry
- CO2 Monitoring
11
Q
Treatment for NMD
A
- Non Invasive Ventilation
- Oxygen therapy
- t-IPPV
12
Q
What is tIPPV?
A
Tracheostomized Intermittent Positive Pressure Ventilation
