NAPLEX Counseling Points Flashcards

1
Q

Quinolones Can Cause: (6 things)

A
  1. CNS effects (includes seizures)
  2. Hypo/Hyper Glycemia
  3. Peripheral Neuropathy
  4. Photosensitivity
  5. QT prolongation
  6. Tendon inflammation (or rupture)
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2
Q

Can Quinolones be used in pregnancy?

A

No, avoid also in breastfeeding and in children

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3
Q

Macrocodes Can Cause: (2 things)

A

GI Upset
QT prolongation

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4
Q

Should pregnant patients take tetracycline?

A

No, avoid in pregnancy, breastfeeding, and children < 8 y

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5
Q

How should you take oral doxycycline ?

A

full glass of water and remain upright for 30 minutes after to avoid GI irritation

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6
Q

Can Bactrim be used in pregnancy?

A

No, do not use in pregnancy or breastfeeding.

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7
Q

Bactrim side effects: (2)

A

photosensitivity
crystals in urine (full glass of water)

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8
Q

How long should you avoid alcohol after taking Metronidazole?

A

3 days

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9
Q

Metronidazole can cause (2 side effects)

A

Nausea

Metallic taste in the mouth

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10
Q

What can you do to decrease Nausea in Nitrofurantoin?

A

Take with food

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11
Q

Nitrofurantoin can cause (2 side effects)

A

Nausea

Discolored urine (brown - harmless)

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12
Q

What do you counsel on with Mupirocin Nasal Ointment?

A

1/2 ointment from the tube into 1 nostril and repeat on the other. press down on both nostrils at the same time. Do this multiple times for one minute.

  • Wash hands after use
  • Can cause burning and itching in the nose
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13
Q

Azole Antifungals can cause? (2 points)

A

Liver damage
&
Prolong QT (except isavuconazonium)

All have many DDI

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14
Q

What is unique about Cresemba (Isavuconazonium)?

A

does not prolong QTc

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15
Q

How should you take itraconazole tablets/capsules?

A

With food

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16
Q

How should you take itraconazole solution?

A

on an empty stomach

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17
Q

What do both itraconazole and ketoconazole need for best absorption?

A

ACIDIC environment! need to space out PPI’s by at least 2 hours.

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18
Q

How do you best take Posaconazole (Noxafil)?

A

take the tablets with food

take the suspension: full meal or a liquid nutritional supplement

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19
Q

When is it best to take voriconazole (Vfend0

A

best on an empty stomach, at least one hour before or after meals.
Store reconstituted suspension at room temperature

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20
Q

Voriconazole can cause (2 side effects)

A

photosensitivity and vision changes

21
Q

What should patients know about the effects of Terbinafine?

A

can take several months after finishing treatment to see the full benefit. (takes time for new healthy nails to grow in place of the infected ones)

22
Q

When can a patient start Oseltamivir (tamiflu) and what can it cause?

A

Should start within two days of symptom onset.

CAN cause delirium

23
Q

When should a patient start acyclovir and valacyclovir?

A

within 24 hours of symptom onset

24
Q

What is an important thing to tell patients about acyclovir topical cream?

A

Can cause temporary burning or stinging

25
Q

Lactic Acidosis can occur in all (HIV Class)

A

NRTIs (ZDS <3 LATTE)

26
Q

Abacavir requires ?

A

HLAB 5701 Allele (increased risk of hypersensitivity reaction)

27
Q

A patient comes in with darkened spots on their hands and the soles of their feet. What HIV medication is most likely causing this?

A

Emtricitabine (Emtriva)

28
Q

TDF and TAF can cause (2 things)

A

Kidney Impairment

Low Bone Density/Fracture risk

29
Q

All INSTI’s interact with this type of medication and requires spacing?

A

Antacids! take 2 hours before or 6 hours after

(-tegravir BRED)

30
Q

All NNRTIs Can cause (2 things)

A

Rash/ Severe

Hepatotoxicity

(-vir- , REDDEN)

31
Q

Efavirenz, an NNRTI, should be taken at what time of day?

A

Night and on an empty stomach to decrease side effects (CNS)

  • Depression and psychosis, confusion, abnormal dreams (should all improve within 2 -4 weeks )
32
Q

All Protease inhibitors should be taken with food EXCEPT:

A

Fosamprenavir po SOL

33
Q

When looking at a patient with HIV’s labs you see they have both elevated glucose and TG. You have also noticed some body fat redistribution. WHAT HIV Class could be causing this?

A

Protease Inhibitors (-navir)

34
Q

If a patient is taking RITONAVIR with Atazanavir or Darunavir what should they do?

A

Make sure to take them at the SAME TIME

35
Q

Atazanavir can cause: (2 things)

A

Hyperbilirubinemia and is CI with acid suppressing medications

36
Q

If a patient has an allergy to X darunavir, fosamprenavir, and tipranvir should be used with caution:

A

Sulfa

37
Q

What fruit should be avoided in all Statins?

A

Grapefruit due to its effects on CYP3A4 (increased levels)

38
Q

Ezetimibe can cause (2 things)

A

Muscle damage and liver damage

39
Q

What kind of administration/storage/SE can PCSK9 inhibitors cause?

A

Admin: SUBQ (thigh, abdomen, upper arm)

Store: in fridge, allow to warm up to room temp before injecting. Can be kept at room temp for 30 days

Can cause: injection site reactions, Allergic Rxn

40
Q

What are 3 important points for Bile acid sequestrants (admin, se x 2)

A

take at meal time with plenty of fluids

can cause constipation

reduces ADEK vitamin absorption

41
Q

Fibrates can cause (2 things)

A

Pancreatitis

Cholelithiasis (gallstones)

42
Q

A patient is experiencing flushing while taking niacin. How can we help them?

A

Take ASA 325 or Ibuprofen 200 30 - 60 minutes before the dose.
Avoid spicy foods and hot liquids.

43
Q

Thiazides, BB, and Clonidine can cause:

A

Sexual Dysfunction

44
Q

A patient comes in with gingival hyperplasia. What class of medication may have caused this?

A

CCB (non DHP>DHP)

45
Q

Nitroglycerin products have a known DDI with?

A

PDE5- inhibitors (increases hypotension )

46
Q

A patient tells you that when they take their SL Nitrostat they get a slight burning and tingling feeling.
They ask you if this needs to occur to know that it is working?

A

No, this feeling is not a sign of how the medication is working

47
Q

What counseling should be given to patient taking home a Nitro spray?

A

DO NOT SHAKE. spray onto or under the tongue. do NOT inhale the spray and try not to swallow too quickly afterward.

48
Q

A patient asks you what they should no when applying nitrobid ointment:

A

measure with the dose card.

it can stain your clothing