Naloxone Flashcards
1
Q
Therapeutic Classification
A
Opioid (narcotic) antagonist
2
Q
Pharmacologic classification
A
Opioid overdose agent
3
Q
Pregnancy Category
A
C
4
Q
Mechanism of Action
A
o Competes with opioid agonist for mu and kappa receptors
• Antagonizes all effects of morphine and other opioids
• Reverse respiratory depression and coma
5
Q
Indications
A
o Opioid overdose
o Postoperatively to reverse opioids given during surgery
6
Q
Contraindictions
A
Hypersensitivity
7
Q
Precautions
A
o Chronic physical dependence to opioids
o Cardiovascular disease
o Seizure disorder
8
Q
Drug Interactions
A
o Reverse all effects of opioids
o Use with tramadol can increase risk of seizure
9
Q
Adverse Effects
A
none
10
Q
Serious Side Effects
A
o Tachycardia o Dysrhythmia o Hypertension o Nausea o Vomiting
11
Q
Nursing Responsibility
A
o Assess respiratory status o Resuscitation equip available o Monitor for signs of withdrawal o Assess vital signs, pain level, pupil size o Be prepared for respiratory arrest
