NA Inhibitors Flashcards
Who invented prontosil?
Gerhard domgark
Route of administration of Sulfonamide?
Oral & IV & IM & Topical
Route of administration of Sulfasalazine?
Oral
Route of administration of Sulfadiazine?
Topical
3 Contraindications of sulfonamides ?
G6PD patients
Kidney insufficiency
Newborns (& pregnant)
What category of tetragenicity is Sulfonamide ?
D
What category of tetragenicity is Trimethoprim ?
D
Which 2 bacteria developed risestance to co-trimoxazole
Travler’s diarrhea E.coli
Streptococcus pharygitis
What does quinolone work on?
Type II topoisomerase
(II / Gyrase > G- & IV > G+)
Antibiotics that treats both MRSA and P.aeruginosa
Delafloxacin
As we progress through generations of quinolones safety ………….?
Increase
As we progress through generations of Cephalosporins safety ………….?
Decrease
What category of teratogenicity are quinolones ?
C/D