NA Inhibitors Flashcards

1
Q

Who invented prontosil?

A

Gerhard domgark

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2
Q

Route of administration of Sulfonamide?

A

Oral & IV & IM & Topical

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3
Q

Route of administration of Sulfasalazine?

A

Oral

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4
Q

Route of administration of Sulfadiazine?

A

Topical

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5
Q

3 Contraindications of sulfonamides ?

A

G6PD patients
Kidney insufficiency
Newborns (& pregnant)

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6
Q

What category of tetragenicity is Sulfonamide ?

A

D

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7
Q

What category of tetragenicity is Trimethoprim ?

A

D

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8
Q

Which 2 bacteria developed risestance to co-trimoxazole

A

Travler’s diarrhea E.coli
Streptococcus pharygitis

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9
Q

What does quinolone work on?

A

Type II topoisomerase
(II / Gyrase > G- & IV > G+)

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10
Q

Antibiotics that treats both MRSA and P.aeruginosa

A

Delafloxacin

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11
Q

As we progress through generations of quinolones safety ………….?

A

Increase

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12
Q

As we progress through generations of Cephalosporins safety ………….?

A

Decrease

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13
Q

What category of teratogenicity are quinolones ?

A

C/D

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