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GI Pharm > N/V > Flashcards

N/V Flashcards

1
Q

Serotonin antagonists

A

Dolasetron

Granisetron

Ondansetron

Palanosetron

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2
Q

Serotonin antagonists worrisome side effect

A

Dolasetron- prolongs QT interval

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3
Q

Serotonin antagonists long half life

A

Palonosetron***

Granisetron (sustained release formula)

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4
Q

Neurokinin (substance P) antagonists

A

Aprepitant

Fosaprepitant

Netupitant

Rolapitant

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5
Q

Neurokinin antagonist- prophylaxis B4 surgery

A

Aprepitant

Fosaprepitant

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6
Q

NK1 antagonist longer half life

A

Netupitant

Rolapitant

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7
Q

Histamine antagonist

A

Diphenhydramine

Dimenhydrinate

Doxylamine***

Hydroxyzine

Promethazine

Meclizine

Cyclizine

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8
Q

H1 antagonists for vertigo/motion sickness

A

Meclizine

Cyclizine

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9
Q

H1 antagonists longer half life

A

Hydroxzine***

Promethazine

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10
Q

Dopamine antagonists

A

Phenothiazine**
Chlorpromazine
Perphenazine
Prochlorperazine

Metoclopramide

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11
Q

Metoclopramide other use

A

Stimulates a ach actions enhancing GI motility and increases LES tone

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12
Q

Muscarinic antagonists

A

Scopolamine

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13
Q

Canabinoid agonists

A

Dronabinol

Nabilone

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14
Q

Cannabinoid unique trait

A

Reserved for treatment of resistant CINV

On a bunch of stuff and still struggling-add these on

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15
Q

CINV high-emetogenic regimen

A

NK1 antagonist
Serotonin antagonist
Corticosteroids (dexamethasone)

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16
Q

CINV moderate-emetogenic regimen

A

Serotonin antagonist

Corticosteroid (dexamethasone)

17
Q

CINV low-emetogenic

A

Corticosteroids (dex) OR

Serotonin antagonist OR

Metoclopramide OR

Prochlorperazine

GI Pharm (9 decks)

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