Drug Class Indications

Question 1

5-ASA

Answer 1

UC

Mild to moderate, active UC and maintenance of remission

Question 2

5-ASA exceptions

Answer 2

Olsalazine- maintenance only

Balsalazide- treatment only of active disease

Question 3

TNF-alpha

Answer 3

All used to get to remission and keep them there

Moderate to severe

Question 4

Alpha-4 inhibitors

Answer 4

Moderate to severe, severe resistance and maintenance therapy for both drugs

Approved for MS too (Nat)

Don’t pick for mild, but do if it’s progressing d/t failing therapy

Question 5

TB tests needed for which two drug classes?

Answer 5

TNF-alpha

IL-12/23 inhibitors

Why? Side effect of infection

Question 6

IL-12/23 inhibitor

Answer 6

Moderate to severe/resistant CD and maintenance too

Question 7

Corticosteroids

Answer 7

Acute and/or severe UC/CD uncontrolled by other drugs

Acute hospital flares (add to other drug they’re already on)

Use for as short amount of time as possible

Not for maintenance unless steroid-dependent