Mycology and antifungals

Question 1

Fungi

Answer 1

Eukaryotic, chitinous cell wall, heterotrophic (eats other plants or animals for energy and nutrients)

Question 2

Yeasts are small single celled organisms that divide by _______

Answer 2

budding

Question 3

Moulds form multicellular h____ and spores

Answer 3

hyphae

Question 4

What are dimorphic fungi

Answer 4

fungi that switch between being yeast and mould when conditions suit

Question 5

Fungi plasma membrane contains e_____ (instead of cholesterol in humans)

Answer 5

ergosterol

Question 6

When there are storms/lightning, sensitised people may develop a____ due to mould spores

Answer 6

asthma

Question 7

Mucosal c_______ is a common and recurrent disease causes significant morbidity

Answer 7

candidiasis

Question 8

Mucosal candidiasis is commonly known as t____

Answer 8

thrush

Question 9

Dermatophyte infection are spread…

Answer 9

human-human or animal-human

Question 10

Ringworm is/isn’t a worm!

Answer 10

Isn’t - its a fungi

Question 11

Treatment of dermatophytes

Answer 11

topical or oral azoles or terbinafine

Question 12

Dimorphic fungi release c______ and can be life-threatening

Answer 12

chlamydia

Question 13

Dimorphic fungi spores convert to ____ form at 37 degrees

Answer 13

yeast

Question 14

Coccidioides are most common in warm, arid conditions in…

Answer 14

South West USA

Question 15

Invasive candidiasis is mostly due to infection of p______ devices or intra-abdominal disease

Answer 15

prosthetic

Question 16

Cryptococcus causes acute or chronic m_____ in patients with reduced cell mediated immunity

Answer 16

meningitis

Question 17

Cryptococcus is associated with bird guano and r____ w___

Answer 17

rotting wood

Question 18

Invasive aspergillosis is normally associated with profound immunocompromise or severe v___ infection

Answer 18

viral

Question 19

What is the treatment of choice for invasive aspergillosis?

Answer 19

Voriconazole

Question 20

Mucoraceous moulds (zygomyctes) are rare but causes rapidly progressive infection that cross t____ planes

Answer 20

tissue

Question 21

Mucoraceious moulds need aggressive a_____ t_____ and surgery for optimal outcomes

Answer 21

antifungal therapy

Question 22

Pneumocystis jirovecii causes a p______ with severe hypoxia in the immunocompromised

Answer 22

pneumonitis

Question 23

Fungi can be challenging to treat because…

Answer 23

We have relatively few classes of agent effective against them