Mycobacterium Leprae (tejidos) Flashcards

1
Q

Tipo de bacteria que es

A

Bacilo ácido alcohol resistente

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2
Q

Características (2)

A

Intercelular
Forma de paquete de cigarros

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3
Q

Qué provoca?

A

Lesiones granulomatosas crónicas de la piel y daño en tejido nervioso periférico

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4
Q

Cuál es el reservorio natural?

A

Los armadillos

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5
Q

Epidemiología

A

Contacto íntimo y prolongado con el bacilo
Inhalación

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6
Q

Tipos de lepra

A

Tubérculoide

Lepromatosa

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7
Q

Lepra benigna

A

Lepra tuberculoide

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8
Q

De qué depende el tipo de lepra

A

Del sistema inmune

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9
Q

Factores de virulencia

A

Tropismo por células endoteliales, Schwan

Antígeno específico PGL1: Glicolipido fenólico

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10
Q

Nombre del antígeno específico

A

PGL1 glicolípido fenólico

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11
Q

Tipo de respuesta inmune que provoca la lepra tuberculoide

A

Th1 = IL 2 e INFgamma

Celular por TCD4

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12
Q

Respuesta en única causada por lepra lepromatosa

A

Th2= forma granuloma
IL 4

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13
Q

Patogénesis

A

Inflamación nervios periféricos = anestesia general

Lesiones granulomatosas crónicas

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14
Q

Características lepra TUBERCULOIDE (6)

A

Menos agresiva
Placas eritematosas con máculas y hipocrómicas
Lesiones cutáneas bien localizadas
borde activo
Centro pálido
Anestesia

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15
Q

Características diagnóstico lepra truberculoide

A

Baciloscopia negativa, intradermorreacción: lepromina positiva

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16
Q

Características de lepra LEPROMATOSA (7)

A

Invasiva
Lesion sistémica y lenta
Pérdida total de cejas, pestañas y vello corporal
Facias leonina
Nódulo subcutáneos
Pérdida del tabique nasal
Mano en garra

17
Q

Diagnóstico de lepra Lepromatosa

A

Ziehl Neelsen
Reacción de Mitsuda y Fernández