Myasthenia Gravis Flashcards

1
Q

Pyridostigmine (Mestinon)

A

A) Acetylcholinesterase Inhibitor

B)
1. Myasthenia gravis

C)
IR: 60 - 720 mg daily (divided doses)
CR: 180 - 540 mg ONCE or TWICE daily

D)
1. CHOLINERGIC CRISIS (overtreatment - excessive sweating, urination, bradycardia)
2. RENAL (lower doses)
NO hepatic

E)
Labels: A* (swallow whole - CR)
S/E:
- nausea and vomiting, diarrhoea, abdo cramps
- increased salivation and sweating
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