Mutations Flashcards
What are gene mutations?
Involve the change in DNA base sequence of chromosomes
What is the type of errors?
- Substitution
- Deletion
What is the substitution?
One base is substituted with another
ATGCCT -> ATTCCT
What is deletion?
One base is deleted
ATGCCT - ATCCT
What does the order of the DNA bases in a gene determine?
Order of amino acids in a particular protein
What happens if there is a mutation in DNA bases of gene?
Sequence of amino acid it codes for could be altered
How do all substitution mutations result in a change to the amino acid?
Degenature nature of the genetic code - some amino acids are coded by more than one DNA base triplet
Some code for the same amino acid
How will the deletion of bases change the amino acid sequence?
Changes the number of bases present
Cause a sift in all bases triplets after it
Examples of mutagenic agents
- Ultraviolet radiation
- Ionising radiation
- Some chemicals and some viruses examples of mutagenic agents