mutations Flashcards
mutations
changes in DNA
point mutations
adds or removes a single nucleotide (substitution, insertion, deletion)
substitution mutations
one nucleotide replaces another type of nucleotide (effects= silent, missense, nonsense)
silent
substitution results in a new codon that codes for the same amino acid
missense
substitute results in a different amino acid
nonsense
substitution results in creation of a stop codon
frameshift mutations
one or two nucleotides being added or removed altering every codon from that point onwards, resulting in loss of function
chromosomal mutations
involves large sections of chromosomes (two forms= polyploidy and block)
polyploidy
when a normally diploid cell acquires one or more additional sets of chromosomes
block mutations
effect large sections of chromosomes, typically multiple genes