Mutation And Genetic Code

Question 0

Missense mutation

Answer 0

Non-synonymous change that alters amino acid identity (often difficult to determine if change is harmful or neutral)

Question 1

Open reading frame

Answer 1

Portion of DNA molecule that when translated into amino acids contains no stop codons

Question 2

Nonsense mutation

Answer 2

Converts a codon encoding an amino acid to a stop codon

Question 3

Frame shift mutation

Answer 3

Insertion or deletion of base pairs to shift the reading frame and eventually produce a premature stop codon

Question 4

In-frame deletion

Answer 4

Loss of one or more amino acids without disrupting the open reading frame

Question 5

Splice junction mutation

Answer 5

Alters or abolishes the specific sequence denoting the site at which the splicing of an intron takes place