Mutation Flashcards
What are the small-scale mutation. There are 5 what are they?
- Point Mutation
- Substitution Mutation
- Inversion
- Insertion
- Deletion
When “one or more bases” in the sequence is REPLACED by the same number of bases
Substitution Mutation
When a base is DELETED from the sequence.
Deletion
When a segment of a chromosome is “reversed end to end”
Inversion
When a base is ADDED to the sequence.
Insertion
A change in one base in the DNA sequence
Point Mutation
Defined as a change in a DNA sequence
Mutation
Effects of small-scale mutation?
- Silent Mutation
- Missense Mutation
- Nonsense Mutation
One of the effects of small-scale mutation: the nucleotide is replaced, but the codon still produces the “same amino acid”.
Silent Mutation
Effects of small-scale mutation: the codon now results in a “STOP” command, truncating the protein at the location where the mutated codon is read
Nonsense Mutation
Effects of small-scale mutation: the codon now results in a “different amino acid, which may or may not significantly alter the protein’s function.
Missense Mutation
Chargaff’s Rules A =_____ and G = ________
A= T
G= C
What are the stop codons
UAA
UAG
UGA
6 Large-scale mutation what are they?
- Deletion
- Duplication
- Inversion
- Insertion
- Translocation
- Nondisjunction
DIDINT
The use of living organisms or their products to modify human health and human environment?
Biotechnology